Breast Cancer Research

Articles Available on Medscape

• Lasofoxifene as a Potential Treatment for Therapy-Resistant ER-Positive Metastatic Breast Cancer
  Should lasofoxifene be considered as a potential treatment for ER-positive metastatic breast cancer that is resistant to endocrine therapy?

  August 02, 2021

• Association Between Menopausal Hormone Therapy, Mammographic Density and Breast Cancer Risk
  What have we learned about the joint effect of menopausal hormone therapy and mammographic density on the risk for breast cancer?

  June 02, 2021

• A Phase Ib/II Study of Xentuzumab, An IGF-Neutralising Antibody, Combined With Exemestane and Everolimus in Hormone Receptor-Positive, HER2-Negative Locally Advanced/Metastatic Breast Cancer
  Did patients with locally advanced or metastatic breast cancer realize improvements in progression-free survival after treatment with this triple combination therapy?

  April 30, 2021

• Invasive Lobular Carcinoma of the Breast: The Increasing Importance of This Special Subtype
  Get up-to-date on the latest research that has advanced our understanding of the pathology and management of this common subtype of breast cancer.

  March 30, 2021

• Navitoclax Enhances the Effectiveness of EGFR-Targeted Antibody-Drug Conjugates in PDX Models of EGFR-Expressing Triple-Negative Breast Cancer
  Navitoclax used in combination with EGFR-targeted ADCs could present a potential new treatment option for EGFR-expressing triple-negative breast cancer.

  March 15, 2021

Table of Contents

2021 - 23 (1)

• Risk of contralateral breast cancer according to first breast cancer characteristics among women in the USA, 1992-2016. 

  February 17, 2021

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• Multi-modal imaging of high-risk ductal carcinoma in situ of the breast using C2Am: a targeted cell death imaging agent. 

  February 17, 2021

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• Identification of MFGE8 and KLK5/7 as mediators of breast tumorigenesis and resistance to COX-2 inhibition. 

  February 15, 2021

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• Comparative validation of the BOADICEA and Tyrer-Cuzick breast cancer risk models incorporating classical risk factors and polygenic risk in a population-based prospective cohort of women of European ancestry. 

  February 15, 2021

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• FGFR1 amplification or overexpression and hormonal resistance in luminal breast cancer: rationale for a triple blockade of ER, CDK4/6, and FGFR1. 

  February 12, 2021

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• Molecular analyses of triple-negative breast cancer in the young and elderly. 

  February 10, 2021

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• The longitudinal relationship between immune cell profiles and frailty in patients with breast cancer receiving chemotherapy. 

  February 05, 2021

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• Impact of post-diagnosis weight change on survival outcomes in Black and White breast cancer patients. 

  February 04, 2021

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• In modern times, how important are breast cancer stage, grade and receptor subtype for survival: a population-based cohort study. 

  February 01, 2021

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• Effects of neoadjuvant chemotherapy on the contralateral non-tumor-bearing breast assessed by diffuse optical tomography. 

  January 31, 2021

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• Infiltrating immune cells in benign breast disease and risk of subsequent invasive breast cancer. 

  January 30, 2021

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• Patterns of treatment with everolimus exemestane in hormone receptor-positive HER2-negative metastatic breast cancer in the era of targeted therapy. 

  January 29, 2021

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• Correction to: Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression. 

  January 28, 2021

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• MicroRNA-3613-3p functions as a tumor suppressor and represents a novel therapeutic target in breast cancer. 

  January 25, 2021

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• Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy. 

  January 23, 2021

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• PDGFRβ is an essential therapeutic target for BRCA1-deficient mammary tumors. 

  January 21, 2021

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• Characteristics and outcome of breast cancer-related microangiopathic haemolytic anaemia: a multicentre study. 

  January 19, 2021

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• A phase Ib/II study of xentuzumab, an IGF-neutralising antibody, combined with exemestane and everolimus in hormone receptor-positive, HER2-negative locally advanced/metastatic breast cancer. 

  January 15, 2021

  • [ Full-text on Medscape ]
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• Targetable alterations in invasive pleomorphic lobular carcinoma of the breast. 

  January 13, 2021

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• Multiplex immunofluorescence to measure dynamic changes in tumor-infiltrating lymphocytes and PD-L1 in early-stage breast cancer. 

  January 07, 2021

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• High B3GALT5 expression confers poor clinical outcome and contributes to tumor progression and metastasis in breast cancer. 

  January 07, 2021

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• NRG1 fusions in breast cancer. 

  January 07, 2021

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• Differential PD-1/LAG-3 expression and immune phenotypes in metastatic sites of breast cancer. 

  January 07, 2021

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• Invasive lobular carcinoma of the breast: the increasing importance of this special subtype. 

  January 07, 2021

  • [ Full-text on Medscape ]
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• Acquired mutations and transcriptional remodeling in long-term estrogen-deprived locoregional breast cancer recurrences. 

  January 06, 2021

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