Diabetes

Articles Available on Medscape

• Risk Factors for Cardiovascular Disease in Type 1 Diabetes
  Hyperglycemia and age may be significant contributors to the risk of cardiovascular events among patients with type 1 diabetes.

  May 24, 2016

• Short-term Cold Acclimation Recruits Brown Adipose Tissue in Obese Humans
  Find out how short-term exposures to cold affects the recruitment of brown adipose tissue -- and learn how this activity may improve glucose metabolism.

  May 10, 2016

• Maternal Glucose and Fatty Acid Kinetics and Infant Birth Weight in Obese Women With Type 2 Diabetes
  Maternal glucose, fatty acids, and birth weight -- what is the relationship? This study examines the possible connection among obese women with pre-gestational type 2 diabetes.

  April 26, 2016

• Variations in Brain Volume and Growth in Young Children With Type 1 Diabetes
  How does early-onset diabetes impact brain development? This study takes a look at the variations in brain volume among children with type 1 diabetes.

  March 22, 2016

• Type 1 Diabetes - Reaping the Rewards of a Targeted Research Investment
  A special funding program for type 1 diabetes research has led to many exciting advances in the understanding, prevention, and management of this disease.

  March 08, 2016

Table of Contents

2019 -

• Mitochondrial Proton Leak Regulated by Cyclophilin D elevates Insulin Secretion in Islets at Non-Stimulatory Glucose Levels. 

  November 18, 2019

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• Predictive Modeling of Type 1 Diabetes Stages Using Disparate Data Sources. 

  November 18, 2019

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• Tacrolimus-Induced BMP/SMAD Signaling Associates with Metabolic Stress-Activated FOXO1 to Trigger β-Cell Failure. 

  November 15, 2019

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• Impaired Metabolic Flexibility to High-fat Overfeeding Predicts Future Weight Gain in Healthy Adults. 

  November 11, 2019

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• Immunomodulation Followed By Antigen-Specific Treg Infusion Controls Islet Autoimmunity. 

  November 11, 2019

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• Inhibition Of Mitochondrial Calcium Overload By SIRT3 Prevents Obesity Or Age-Related Whitening Of Brown Adipose Tissue. 

  November 11, 2019

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• Myeloid HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A) Reductase Determines Adipose Tissue Inflammation, Insulin Resistance And Hepatic Steatosis In Diet-Induced Obese Mice. 

  November 05, 2019

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• Acyl-ghrelin is Permissive for the Normal Counterregulatory Response to Insulin-induced Hypoglycemia. 

  November 04, 2019

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• CTRP13 Preserves Endothelial Function by Targeting GTP Cyclohydrolase 1 in Diabetes. 

  November 01, 2019

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• High prevalence of a monogenic cause in Han Chinese diagnosed with type 1 diabetes, partly driven by non-syndromic recessive WFS1 mutations. 

  October 28, 2019

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• A Primary Role for Alpha Cells as Amino Acid Sensors. 

  October 25, 2019

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• Atorvastatin Targets the Islet Mevalonate Pathway to Dysregulate mTOR Signaling and Reduce β-cell Functional Mass. 

  October 24, 2019

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• Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors. 

  October 21, 2019

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• RILP Restricts Insulin Secretion Through Mediating Lysosomal Degradation of Proinsulin. 

  October 17, 2019

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• Complement C5a Induces Renal Injury in Diabetic Kidney Disease Via Disruption in Mitochondrial Metabolic Agility. 

  October 17, 2019

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• RNF20 Functions as a Transcriptional Coactivator for PPARγ by Promoting NCoR1 Degradation in Adipocytes. 

  October 11, 2019

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• Fat-Specific Knockout of Mecp2 Upregulates Slpi to Reduce Obesity by Enhancing Browning. 

  October 09, 2019

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• Temporal Analysis of Amylase Expression in Control, Autoantibody Positive, and Type 1 Diabetes Pancreatic Tissues. 

  October 09, 2019

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• Erratum. Hypothesis: Role of Reduced Hepatic Insulin Clearance in the Pathogenesis of Type 2 Diabetes 2019;68:1709-1716. 

  October 09, 2019

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• Longitudinal Pattern of First-Phase Insulin Response Is Associated with Genetic Variants Outside the Class II HLA Region in Children with Multiple Autoantibodies. 

  October 07, 2019

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• Metabolite Profiles of Incident Diabetes and Heterogeneity of Treatment Effect in the Diabetes Prevention Program. 

  October 03, 2019

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• Comparison of Kidney Transcriptomic Profiles of Early and Advanced Diabetic Nephropathy Reveals Potential New Mechanisms for Disease Progression. 

  October 02, 2019

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• The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1. 

  October 02, 2019

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• Metabolomics Identifies a Biomarker Revealing in Vivo Loss of Functional ß-Cell Mass Before Diabetes Onset. 

  September 19, 2019

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• Genome-Wide Association Study on the Early Phase Insulin Response to a Liquid Mixed Meal: Results From the NEO Study. 

  September 19, 2019

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• MCH Regulates SIRT1/FoxO1 and Reduces POMC Neuronal Activity to Induce Hyperphagia, Adiposity and Glucose Intolerance. 

  September 16, 2019

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• Murine Perinatal Beta Cell Proliferation and the Differentiation of Human Stem Cell Derived Insulin Expressing Cells Require NEUROD1. 

  September 13, 2019

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• Glucolipotoxicity, β-Cells, and Diabetes: The Emperor Has No Clothes. 

  September 13, 2019

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• Evaluation of the Genetic Association Between Adult Obesity and Neuropsychiatric Disease. 

  September 10, 2019

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• Diabetic Nephropathy Alters the Distribution of Circulating Angiogenic miRNAs Between Extracellular Vesicles, HDL and Ago-2. 

  September 10, 2019

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• Epigenome-Wide Association Study of Incident Type 2 Diabetes in a British Population: EPIC-Norfolk Study. 

  September 10, 2019

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• Subcutaneous Adipose Tissue and Systemic Inflammation are Associated with Peripheral But Not Hepatic Insulin Resistance in Humans. 

  September 06, 2019

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• Mitochondrial Uncoupling Coordinated With PDH Activation Safely Ameliorates Hyperglycemia Via Promoting Glucose Oxidation. 

  August 30, 2019

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• Repositioning Glucagon Action in the Physiology and Pharmacology of Diabetes. 

  June 09, 2019

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• A Peripheral Blood DNA Methylation Signature of Hepatic Fat Reveals a Potential Causal Pathway for Non-Alcoholic Fatty Liver Disease. 

  February 22, 2019

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