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How will novel biologics and immunotherapies impact the treatment of meningioma? This review looks at current strategies and avenues for future therapeutic development.
This review examines grade II and III meningiomas from a genomic perspective. What are the implications of their genomic and immunological characteristics in terms of future therapeutics?
A combined approach of subtotal resection followed by stereotactic radiosurgery for large vestibular schwannoma is associated with good clinical and functional outcomes and tumor control.
According to this review, a keyhole neurosurgical approach for large vestibular schwannomas is associated with greater extent of resection and low rates of postoperative complications.
With its ability to disrupt the blood-brain barrier, MR-guided focused ultrasound holds significant promise as a noninvasive treatment option to achieve targeted drug delivery to brain tumors.
This study investigated whether patients with preexisting depression have poorer outcomes following lumbar fusion. Does preoperative depression increase the use of postoperative opioids?
Are minimally invasive lateral lumbar interbody fusion and anterior lumbar interbody fusion viable strategies for achieving closed reduction of grade II lumbar spondylolisthesis?
Which patients were the most and the least satisfied following surgery for degenerative lumbar spondylolisthesis? The findings of this study highlight several key factors that may impact outcomes.
The authors review and compare the endoscopic endonasal and traditional open microsurgical approaches to craniopharyngioma surgery. How should a decision be made as to the appropriate strategy?
Are preoperative radiological findings in pediatric patients with obstructive hydrocephalus useful for predicting overall outcome following shunt insertion?
The authors describe the use of spinal laser interstitial thermotherapy with percutaneous spinal stabilization for the treatment of epidural spinal cord compression caused by metastatic tumors.
Does the presence of cerebral tau protein equal a diagnosis of CTE? Is CTE a progressive disorder? These and other common questions regarding CTE are addressed in this article.
A better understanding of the pathology and molecular changes associated with sports-related head trauma may lead to innovations in imaging techniques and new biomarkers, according to this article.
This article reviews the diagnosis of sports-related concussions both on and off the field, and presents therapeutic strategies for neurosurgeons as well as a multidisciplinary health care team.
This study investigated the utility of endoscopic foraminotomy for targeted revision surgery in patients with persistent radiculopathy following lumbar fusion surgery.
This study demonstrates that 3D ultrasound can be effectively used as a stand-alone navigation modality during the resection of brain tumors--without the need for preoperative MRI guidance.
High-field 7-T MRI shows promise as a noninvasive tool for evaluating three markers for Alzheimer's disease: neuroanatomical atrophy, characterization of hypointensities, and microinfarcts.
This case series demonstrates the utility of intraoperative ultrasonography in localization of peripheral nerve tumors and neuromas, limiting the need for extensive dissection.
Mission Statement:
As the first peer-reviewed, electronic, topic-based publication of the American Association of Neurological Surgeons, the internationally recognized spokesorganization of neurosurgery, the mission of Neurosurgical Focus is to present new ideas and techniques, as well as fundamental scientific concepts in a timely and accessible fashion.
