JCO Precision Oncology

Articles Available on Medscape

• Tumor Genomic Profiling Practices and Perceptions 
  A survey of physicians provides insight into tumor profiling practices and the factors associated with genomic profiling study participation.

  January 01, 2021

• Implications of Incidental Germline Findings Identified In the Context of Clinical Whole Exome Sequencing for Guiding Cancer Therapy 
  Could the identification of incidental germline mutations provide cancer risk information and help guide treatment decisions?

  December 18, 2020

• Mutation Rates in Cancer Susceptibility Genes in Patients With Breast Cancer With Multiple Primary Cancers 
  The findings from this study further support the need for multigene panel testing in patients with breast cancer and other primary cancers.

  October 09, 2020

• Genomic Profiles of De Novo High- and Low-Volume Metastatic Prostate Cancer 
  A better understanding of the genomic profiles of de novo metastatic prostate cancer could help inform future trial designs.

  September 15, 2020

• Oncologist Confidence in Genomic Testing and Implications for Using Multimarker Tumor Panel Tests in Practice 
  How do oncologists feel about genomic testing and how likely are they to incorporate it into practice?

  August 13, 2020

• Response of Brain Metastases From PIK3CA-Mutant Breast Cancer to Alpelisib 
  Is the newly approved PI3K-inhibitor alpelisib a safe and effective option for breast cancer patients with brain metastases? A case series provides insight into the treatment response.

  July 30, 2020

• Does Testing Error Underlie Liquid Biopsy Discordance? 
  False-positive and false-negative results with plasma next-generation sequencing are very concerning. Why do they occur and what should be done?

  May 08, 2019

• Comparative Analysis of Durable Responses on Immune Checkpoint Inhibitors Versus Other Systemic Therapies 
  Patients receiving immune checkpoint inhibitors may experience durable response over two times more frequently than those receiving other drug classes.

  April 08, 2019