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Targeting DNA Damage Repair in Small Cell Lung Cancer and the Biomarker Landscape
Areas of investigation for SCLC include identification of predictive biomarkers, effective combinations to overcome resistance, and strategies for immunotherapy.
April 16, 2018
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Current Standards for Clinical Management of Small Cell Lung Cancer
Review the latest on diagnosis, staging, and management of SCLC.
March 15, 2018
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Radiomics in Precision Medicine for Lung Cancer
Potential uses for radiomics in lung cancer include basic image segmentation, outcome modeling, and even the deciphering of genetic signatures.
February 14, 2018
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Blood-Based Tumor Biomarkers in Lung Cancer for Detection and Treatment
Review the roles of circulating tumor cells, circulating tumor DNA, microRNA and other biomarkers for lung cancer management.
February 07, 2018
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Advance in Predictive and Prognostic Marker Assessments in Lung Cancer
Advances in personalized medicine and histologic classification and staging are furthering lung cancer management.
January 31, 2018
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Update on Large Cell Neuroendocrine Carcinoma
Review molecular features and treatment options for large cell neuroendocrine carcinoma of the lung.
January 24, 2018
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Biology and Clinical Significance of Circulating Tumor Cell Subpopulations in Lung Cancer
By identifying protein and genetic markers on CTCs, liquid biopsies may change the landscape of NSCLC management.
January 17, 2018
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The Clinical Utility of Circulating Tumour Cells in Patients With Small Cell Lung Cancer
Learn how CTCs can be diagnostic, prognostic, and predictive biomarkers in SCLC.
January 10, 2018
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Immunotherapy for Malignant Pleural Mesothelioma
Review checkpoint blockade, immunotoxin, oncolytic viral, and adoptive cell therapies for malignant mesothelioma.
January 03, 2018
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Diagnostic and Prognostic Biomarkers for Malignant Mesothelioma
Although validation is needed, these biomarkers show the most promise in malignant mesothelioma.
December 27, 2017
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Integrating Immunotherapy Into Chemoradiation Regimens for Medically Inoperable Locally Advanced Non-Small Cell Lung Cancer
Clinicians should consider timing and toxicities when adding a checkpoint inhibitor to chemoradiotherapy for NSCLC.
December 20, 2017
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Clinical Experiences of Combining Immunotherapy and Radiation Therapy in Non-Small Cell Lung Cancer
Review the rationale and preclinical evidence for combining radiation and immunotherapy in NSCLC.
December 13, 2017
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How to Diagnose Pulmonary Nodules: From Screening to Therapy
Review screening of pulmonary nodules to maximize early detection and minimize over-diagnosis of lung cancer.
June 13, 2017
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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors for the Treatment of Central Nervous System Metastases From Non-Small Cell Lung Cancer
Are TKIs effective for treating brain metastases associated with NSCLC? Do newer generation TKIs show activity for intracranial disease?
May 12, 2017
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Liquid Biopsy Based Biomarkers in Non-Small Cell Lung Cancer for Diagnosis and Treatment Monitoring
What can circulating tumor cells, circulating free DNA, and exosomes and tumor-educated platelets tell us about the status of NSCLC?
April 13, 2017
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Histopathological Transformation to Small-Cell Lung Carcinoma in Non-Small Cell Lung Carcinoma Tumors
Is it time to re-biopsy? Deterioration during targeted therapy may indicate transformation of NSCLC to SCLC.
December 01, 2016
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Tumor Lymphocytic Infiltration in Non-Small Cell Lung Cancer
Research is defining the role of tumor-infiltrating lymphocytes in the development, progression, and prognosis of NSCLC.
November 17, 2016
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Prognostic Value of the Expression of Estrogen Receptor Beta in Patients With Non-Small Cell Lung Cancer: A Meta-analysis
What impact does estrogen receptor beta overexpression have on NSCLC survival?
November 03, 2016
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Is Surgery Still the Optimal Treatment for Stage I Non-Small Cell Lung Cancer?
Should stereotactic ablative radiotherapy be considered for early stage NSCLC?
October 20, 2016
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Prognostic Value of Lymph Node Ratio in Patients With Pathological N1 Non-Small Cell Lung Cancer: A Systematic Review With Meta-analysis
Can lymph node ratio predict survival and recurrence in patients with NSCLC?
August 22, 2016
