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Special Features of Total Knee Replacement in Hemophilia
Total knee replacement is frequently needed by hemophilia patients and greatly improves their quality of life, but it carries a higher risk of bleeding and infection for hemophiliacs than it does for osteoarthritis sufferers. . .
January 23, 2014
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Is There a Role for Allogeneic Transplantation in Chronic Myeloid Leukemia?
The future for patients with CML has become so much brighter over the past decade but new issues continually emerge. Find out more.
January 09, 2014
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The Emerging Role of Ibrutinib in the Treatment of Chronic Lymphocytic Leukemia
A first-in-class agent for patients with relapsed or refractory chronic lymphocytic leukemia could be a game changer. Find out why.
December 23, 2013
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Should Elderly Patients With Higher-Risk Myelodysplastic Syndromes Undergo Allogeneic Hematopoietic Stem Cell Transplantation?
Find out more about myelodysplastic syndromes and treatment risks in the elderly.
November 22, 2013
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Treatment of Elderly Patients With Chronic Lymphocytic Leukemia
Find out what can be done to improve the management of elderly patients with CLL.
October 23, 2013
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Fertility Issues Following Hematopoietic Stem Cell Transplantation
Infertility is common after myeloablative HSCT conditioned with total body irradiation and high doses of gonadotoxic drugs, but today there are good possibilities for fertility preservation.
September 23, 2013
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Preventing Thrombophilia-Related Complications of Pregnancy
Management of thrombophilia often involves anticoagulant therapy; however, use of these agents during pregnancy is challenging.
August 12, 2013
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'Use It Again!'
A pattern of relapse followed by further therapy is prevalent in patients with indolent lymphoid malignancies indicating the need for additional effective salvage therapies.
July 12, 2013
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Atypical Lymphoid Proliferations
Lymphoid proliferations are traditionally thought to be either benign conditions (reactive hyperplasia and lymphadenitis) or malignant lymphomas, but what if findings are atypical?
June 11, 2013
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Bendamustine for Non-Hodgkin Lymphoma
Professor John Gribben shares thoughts on treatment strategies for non-Hodgkin lymphoma in this interview.
May 10, 2013
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Immunomodulatory Drugs in Multiple Myeloma
We've come a long way since the first immunomodulatory agent was approved for use in myeloma. This review will update you on the latest developments.
April 11, 2013
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Understanding the Molecular Biology of Myeloma and Its Therapeutic Implications
This review explores the molecular biology of myeloma and identifies how genetic lesions can be used to define high- and low-risk patient groups.
March 11, 2013
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Molecular Genetics of High-Risk Chronic Lymphocytic Leukemia
Find out about next-generation sequencing studies that have revealed several novel genetic alterations in high-risk CLL.
February 10, 2013
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Sequential or Combination Therapy for Multiple Myeloma
Is multiple myeloma treatment less toxic when treatment is sequential?
January 10, 2013
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The Emerging Role of PET in Hodgkin Lymphoma Patients Receiving Autologous Stem Cell Transplant
How do results of positron emission tomography before and after SCT affect lymphoma outcomes?
December 11, 2012
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Augmentation of Anti-tumor Immunity by Adoptive T-Cell Transfer After Allogeneic Hematopoietic Stem Cell Transplantation
Find out more about the development of novel post-HCT therapies for patients who are at high risk for disease recurrence following HCT.
November 12, 2012
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Genetic Biomarkers in Acute Myeloid Leukemia
Improvements in AML biomarkers may lead to better outcomes. Find out why.
October 12, 2012
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Signaling Pathways Activated by the B-Cell Receptor in Chronic Lymphocytic Leukemia
In CLL, how can BCR signaling profiles help to identify signaling markers useful for patient management?
August 30, 2012
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EPHA3 as a Novel Therapeutic Target in the Hematological Malignancies
The Eph receptors are the largest family of tyrosine kinases and are of increasing interest in developmental therapeutics.
July 30, 2012
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Treating Venous Thromboembolism in Patients With Cancer
When is pre-emptive VTE therapy indicated for high-risk patients with cancer?
May 30, 2012