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Biologics: The Next-Generation Therapeutics for Analgesia?
Current therapies for the treatment of chronic pain conditions are inadequate, and there's an urgent need for more effective analgesics. Are biologic agents, such as monoclonal antibodies, the answer?
November 04, 2011
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An Update on the Pharmacotherapy of Attention-Deficit/Hyperactivity Disorder in Adults
This article presents an overview of the effectiveness and dosing parameters of the various agents available and currently under investigation for treatment of adult ADHD.
October 12, 2011
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Advances in Revascularization for Acute Ischemic Stroke Treatment
A discussion of the wide variety of treatment options available for acute ischemic stroke, including new thrombolytic and direct fibrinolytic agents, and devices for mechanical clot retrieval.
September 20, 2011
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Cell Replacement Therapy for Parkinson's Disease
Cell replacement therapy offers great promise as the future of regenerative medicine in Parkinson's disease. This article looks at the latest advances and clinical trial results.
September 13, 2011
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Complementary and Alternative Medicine Therapies in Mood Disorders
Many patients turn to complementary and alternative medicine therapies for the treatment of depression and anxiety. Can they help?
July 27, 2011
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Cell-Based Therapies for Parkinson's Disease
Dopaminergic cell transplantation may provide new hope for Parkinson's sufferers--if a suitable long-term source of transplantable dopaminergic neurons can be found.
June 22, 2011
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Diet and Alzheimer's Disease Risk Factors or Prevention
Many dietary factors have been postulated to play a role in the prevention of cognitive decline, including various vitamins, dairy products, fatty acids, and antioxidants. What's the current evidence?
May 20, 2011
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Plasma Cholesterol and Risk for Late-Onset Alzheimer's Disease
Is hypercholesterolemia a risk factor for Alzheimer's? Studies have been contradictory--and controversial. This article examines these controversial findings and the molecular mechanisms behind them.
April 15, 2011
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Principles of a New Treatment Algorithm in Multiple Sclerosis
How do the newly approved and emerging oral therapies for multiple sclerosis fit into existing treatment strategies? And how might a new treatment algorithm evolve in the near future?
March 18, 2011
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Fingolimod for the Treatment of Relapsing Multiple Sclerosis
The immunosuppressive fingolimod is the first of the long-anticipated oral agents approved for the treatment of relapsing forms of MS. This article reviews its use and safety profile.
March 02, 2011
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Chronic Cerebral Spinal Venous Insufficiency in Multiple Sclerosis
Is there a link between vascular abnormalities and MS? This commentary examines the current thinking and controversy surrounding the role of cerebrospinal venous insufficiency in the etiology of MS.
December 30, 2010
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Epilepsy in the Elderly
Epilepsy, while being the most common serious neurological disorder in the elderly after stroke and dementia, often goes unrecognized, misdiagnosed, or neglected.
December 06, 2010
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Clinical Assessment and Diagnosis of Adults With Attention-Deficit/Hyperactivity Disorder
Diagnostic criteria for ADHD are formulated primarily according to behavior in childhood, although the disorder is prevalent in adults. Would you recognize the symptoms?
November 10, 2010
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Vitamin D and Multiple Sclerosis: What Are the Guidelines for a Reliable Clinical Trial?
Some studies have shown a causal relationship between low serum vitamin D levels and disease activity in MS, but were their methods rigorous enough?
September 24, 2010
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Antidepressants in the Treatment of Stroke
Is it possible that antidepressants could improve outcome from stroke, independent of their psychiatric effect?
August 13, 2010
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Psychopharmacology of Pediatric Bipolar Disorder
This comprehensive literature review evaluates the safety and effectiveness of psychotropic medications in children and adolescents with pediatric bipolar disorder.
July 28, 2010
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Treating Multiple Sclerosis With Monoclonal Antibodies: A 2010 Update
Treatment of MS with monoclonal antibodies has been marked by both progress and setbacks in the past two years. This article critically reviews current mAbs therapies and provides a look ahead.
June 16, 2010
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Glioblastoma Therapy: Going Beyond Hercules Columns
A review of current and potential future treatments for glioblastoma multiforme, the most common primary brain tumor in adults.
May 21, 2010
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Brain Metastases: A Medical Neuro-Oncology Perspective
Brain metastases are the most common neurological complication related to cancer, but therapy remains controversial. This review summarizes current medical and surgical treatments.
April 23, 2010
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Radiofrequency Treatment in Chronic Pain
A comprehensive review of the basis of radiofrequency ablation and some of its most common applications in the management of chronic pain.
March 23, 2010