Respiratory Research

Articles Available on Medscape

• Role of Matrix Metalloproteinases in the Pathogenesis of Idiopathic Pulmonary Fibrosis
  Find out about the involvement of matrix metalloproteinases in the pathogenesis of idiopathic pulmonary fibrosis.

  April 29, 2016

• Birt-Hogg-Dube Syndrome: A Large Single Family Cohort
  Findings from a large single family cohort of Birt-Hogg-Dube syndrome patients sheds some light on this hereditary condition.

  April 15, 2016

• Intralymphatic Immunotherapy of Pollen-Induced Rhinoconjunctivitis
  Is intralymphatic immunotherapy a safe and effective alternative to subcutaneous immunotherapy for rhinoconjunctivitis?

  April 01, 2016

• Utilization Due to Chronic Obstructive Pulmonary Disease and Its Predictors
  How often do COPD patients visit the ED for disease-related care -- and what patient factors may predict a higher risk of hospitalization?

  March 18, 2016

• A Decision Tree to Assess Short-term Mortality After an Emergency Department Visit for an Exacerbation of COPD
  A classification tree may help predict short term mortality risk in patients presenting to the ED with exacerbation of COPD.

  March 04, 2016

Table of Contents

2016 - 17 (1)

• Respiratory symptoms, sleep-disordered breathing and biomarkers in nocturnal gastroesophageal reflux. 

  January 01, 2016

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• Maternal allergic disease history affects childhood allergy development through impairment of neonatal regulatory T-cells. 

  January 01, 2016

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• Pharmacological strategies to reduce exacerbation risk in COPD: a narrative review. 

  January 01, 2016

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• Human primary airway epithelial cells isolated from active smokers have epigenetically impaired antiviral responses. 

  January 01, 2016

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• Serum extracellular vesicular miR-21-5p is a predictor of the prognosis in idiopathic pulmonary fibrosis. 

  January 01, 2016

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• Dose-response to inhaled glycopyrrolate delivered with a novel Co-Suspension��� Delivery Technology metered dose inhaler (MDI) in patients with moderate-to-severe COPD. 

  January 01, 2016

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• Activation of the nicotinamide N-methyltransferase (NNMT)-1-methylnicotinamide (MNA) pathway in pulmonary hypertension. 

  January 01, 2016

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• Metformin attenuates lung fibrosis development via NOX4 suppression. 

  January 01, 2016

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• The impact of comorbidities on productivity loss in asthma patients. 

  January 01, 2016

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• ALK gene copy number gains in non-small-cell lung cancer: prognostic impact and clinico-pathological correlations. 

  January 01, 2016

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• Simvastatin up-regulates adenosine deaminase and suppresses osteopontin expression in COPD patients through an IL-13-dependent mechanism. 

  January 01, 2016

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• Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis. 

  January 01, 2016

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• How to achieve safe, high-quality clinical studies with non-Medicinal Investigational Products? A practical guideline by using intra-bronchial carbon nanoparticles as case study. 

  January 01, 2016

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• High resolution metabolomics to discriminate compounds in serum of male lung cancer patients in South Korea. 

  January 01, 2016

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• Pseudomonas aeruginosa colonization enhances ventilator-associated pneumonia-induced lung injury. 

  January 01, 2016

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• Cardiovascular autonomic alterations in hospitalized patients with community-acquired pneumonia. 

  January 01, 2016

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• Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats. 

  January 01, 2016

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• Induction of pulmonary antibodies against oxidized lipids in mice exposed to cigarette smoke. 

  January 01, 2016

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• The role of circulating thrombospondin-1 in patients with precapillary pulmonary hypertension. 

  January 01, 2016

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• Genes associated with polymorphic variants predicting lung function are differentially expressed during human lung development. 

  January 01, 2016

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• Sarcoidosis activates diverse transcriptional programs in bronchoalveolar lavage cells. 

  January 01, 2016

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• Cigarette smoke alters the ability of human dendritic cells to promote anti-Streptococcus pneumoniae Th17 response. 

  January 01, 2016

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• Distinct emphysema subtypes defined by quantitative CT analysis are associated with specific pulmonary matrix metalloproteinases. 

  January 01, 2016

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• Vimentin dephosphorylation at ser-56 is regulated by type 1 protein phosphatase in smooth muscle. 

  January 01, 2016

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• A proof-of-concept clinical study examining the NRF2 activator sulforaphane against neutrophilic airway inflammation. 

  January 01, 2016

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• A phase II trial evaluating the efficacy and safety of perioperative pirfenidone for prevention of acute exacerbation of idiopathic pulmonary fibrosis in lung cancer patients undergoing pulmonary resection: West Japan Oncology Group 6711��L (PEOPLE Study). 

  January 01, 2016

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• Novel biomarkers for pulmonary arterial hypertension. 

  January 01, 2016

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• Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague-Dawley rats. 

  January 01, 2016

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• Differential effect of mild and severe pulmonary embolism on the rat lung transcriptome. 

  January 01, 2016

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• Airway smooth muscle NOX4 is upregulated and modulates ROS generation in COPD. 

  January 01, 2016

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• An imperfect "PAST" Lessons learned from the National Review of Asthma Deaths (NRAD) UK. 

  January 01, 2016

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• Detection and quantification of epithelial progenitor cell populations in human healthy and IPF lungs. 

  January 01, 2016

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• Weakly acidic pH reduces inflammatory cytokine expression in airway epithelial cells. 

  January 01, 2016

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• Tissue turnover of collagen type I, III and elastin is elevated in the PCLS model of IPF and can be restored back to vehicle levels using a phosphodiesterase inhibitor. 

  January 01, 2016

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• Relative impact of COPD and comorbidities on generic health-related quality of life: a pooled analysis of the COSYCONET patient cohort and control subjects from the KORA and SHIP studies. 

  January 01, 2016

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• Risk factors for an acute exacerbation of idiopathic pulmonary fibrosis. 

  January 01, 2016

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• Risk factors for mortality in patients admitted to intensive care units with pneumonia. 

  January 01, 2016

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• Micron-sized and submicron-sized aerosol deposition in a new ex vivo preclinical model. 

  January 01, 2016

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• Evaluation of the effects of olodaterol on exercise endurance in patients with chronic obstructive pulmonary disease: results from two 6-week crossover studies. 

  January 01, 2016

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• Inflammation and emphysema in cigarette smoke-exposed mice when instilled with poly (I:C) or infected with influenza A or respiratory syncytial viruses. 

  January 01, 2016

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• Diagnostic value of plasma and bronchoalveolar lavage samples in acute lung allograft rejection: differential cytology. 

  January 01, 2016

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• Effects of tiotropium���+���olodaterol versus tiotropium or placebo by COPD disease severity and previous treatment history in the OTEMTO�� studies. 

  January 01, 2016

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• Development of the Pulmonary Arterial Hypertension-Symptoms and Impact (PAH-SYMPACT��) questionnaire: a new patient-reported outcome instrument for PAH. 

  January 01, 2016

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• Acute lung injury induced by whole gastric fluid: hepatic acute phase response contributes to increase lung antiprotease protection. 

  January 01, 2016

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• Pharmacological characterisation of the interaction between glycopyrronium bromide and indacaterol fumarate in human isolated bronchi, small airways and bronchial epithelial cells. 

  January 01, 2016

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• Exposure to common respiratory bacteria alters the airway epithelial response to subsequent viral infection. 

  January 01, 2016

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• Elevated levels of FN1 and CCL2 in bronchoalveolar lavage fluid from sarcoidosis patients. 

  January 01, 2016

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• Role of the ion channel, transient receptor potential cation channel subfamily V member 1 (TRPV1), in allergic asthma. 

  January 01, 2016

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• Surfactant proteins, SP-A and SP-D, in respiratory fungal infections: their role in the inflammatory response. 

  January 01, 2016

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• The role of tissue factor and autophagy in pulmonary vascular remodeling in a rat model for chronic thromboembolic pulmonary hypertension. 

  January 01, 2016

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• Therapeutic effect of budesonide/formoterol, montelukast and N-acetylcysteine for bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation. 

  January 01, 2016

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• A rapid NGS strategy for comprehensive molecular diagnosis of Birt-Hogg-Dub�� syndrome in patients with primary spontaneous pneumothorax. 

  January 01, 2016

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• Investigating the role of MRGPRC11 and capsaicin-sensitive afferent nerves in the anti-influenza effects exerted by SLIGRL-amide in murine airways. 

  January 01, 2016

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• The effect of aclidinium bromide on daily respiratory symptoms of COPD, measured using the Evaluating Respiratory Symptoms in COPD (E-RS: COPD) diary: pooled analysis of two 6-month Phase III studies. 

  January 01, 2016

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• Toxic and adjuvant effects of silica nanoparticles on ovalbumin-induced allergic airway inflammation in mice. 

  January 01, 2016

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• Microvascular reactivity is altered early in patients with acute respiratory distress syndrome. 

  January 01, 2016

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• The up-rise in e-cigarette use - friend or foe? 

  January 01, 2016

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• Ethical considerations of e-cigarette use for tobacco harm reduction. 

  January 01, 2016

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• Airway epithelial cell exposure to distinct e-cigarette liquid flavorings reveals toxicity thresholds and activation of CFTR by the chocolate flavoring 2,5-dimethypyrazine. 

  January 01, 2016

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• Electronic cigarette exposure triggers neutrophil inflammatory responses. 

  January 01, 2016

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• Electronic cigarettes: a survey of perceived patient use and attitudes among members of the British thoracic oncology group. 

  January 01, 2016

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• Occupational and environmental risk factors for chronic rhinosinusitis in China: a multicentre cross-sectional study. 

  January 01, 2016

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• Knowledge about electronic cigarettes and its perception: a community survey, Egypt. 

  January 01, 2016

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• Determinants and impact of suboptimal asthma control in Europe: The INTERNATIONAL CROSS-SECTIONAL AND LONGITUDINAL ASSESSMENT ON ASTHMA CONTROL (LIAISON) study. 

  January 01, 2016

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• Caveolin-1 regulates the expression of tight junction proteins during hyperoxia-induced pulmonary epithelial barrier breakdown. 

  January 01, 2016

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• Ajulemic acid exerts potent anti-fibrotic effect during the fibrogenic phase of bleomycin lung. 

  January 01, 2016

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• Defining a COPD composite safety endpoint for demonstrating efficacy in clinical trials: results from the randomized, placebo-controlled UPLIFT�� trial. 

  January 01, 2016

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• Reviewer acknowledgement 2015. 

  January 01, 2016

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