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Antioxidants and Homocysteine Treatment for Coronary Artery Disease
Antioxidants and the role of lowering homocysteine for the prevention of cardiac problems is discussed by expert Dr. Jane Armitage, professor of clinical trials and epidemiology at Oxford University.
February 10, 2009
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The Goal of Statin Therapy: LDL? CRP? JUPITER Study
JUPITER, the first primary prevention trial that has ever shown a statistically significant reduction in women treated with statins, is discussed by an expert panel.
January 29, 2009
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Heart Failure: Best Inotrope, Best Vasodilator, Indications for Biopsy
Endomyocardial biopsy (EMB) use varies widely even among cardiovascular centers of excellence. Authors explore risks of the procedure and indications for use.
January 27, 2009
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Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus-Eluting Stents (CACTUS)
How does the "crush" technique compare with provisional side-branch T-stenting for the treatment of coronary bifurcations? Is one approach more effective than the other in reducing MACE?
January 23, 2009
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Physicians' Health Study II (PHS II)
Are vitamin C and E supplements individually associated with a reduction in cardiovascular events in male patients who are at a low risk for cardiovascular events?
November 24, 2008
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Justification for the Use of Statins in Prevention: An Intervention Trial Evaluating Rosuvastatin (JUPITER)
Is rosuvastatin associated with a reduction in first major cardiovascular events, as compared with placebo, in apparently healthy patients?
November 21, 2008
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Irbesartan in Heart Failure With Preserved Ejection Fraction Study (I-PRESERVE)
Results and interpretation of the I-PRESERVE study are presented, comparing the role of the angiotensin receptor blocker, irbesartan in HF patients with preserved ejection fraction.
November 20, 2008
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Japanese Stable Angina Pectoris Study (JSAP)
In patients with low-risk stable coronary artery disease, is percutaneous coronary intervention plus medical therapy superior to medical therapy alone?
November 10, 2008
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Impella LP2.5 vs. IABP in Cardiogenic SHOCK (ISAR-SHOCK)
Is a percutaneous left ventricular assist device more effective than an intra-aortic balloon pump in improving hemodynamic support in patients with AMI complicated by cardiogenic shock?
November 07, 2008
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Harmonizing Outcomes With Revascularization and Stents in Acute Myocardial Infarction
Drug-eluting stents (DES) have been shown to be superior to bare-metal stents in a number of settings, but what is the effect of paclitaxel-eluting stents on mid-term outcomes in patients with STEMI?
November 06, 2008
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ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID Use
Gastrointestinal side effects are common in patients treated with NSAIDs and antiplatelet therapies. This article highlights 12 points to remember about the ACCF/ACG/AHA 2008 consensus document.
October 31, 2008
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Vasopressin and Epinephrine vs. Epinephrine Alone in Cardiopulmonary Resuscitation
The prognosis among patients who suffer an out-of-hospital cardiac arrest remains grim. Is the combination of vasopressin and epinephrine superior to epinephrine alone in improving clinical outcomes?
October 30, 2008
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Randomized Trial on Routine vs. Provisional T-Stenting in the Treatment of De Novo Coronary Bifurcation Lesions
Should patients with stable angina due to a bifurcation lesion undergo routine or provisional T-stenting? Is one approach more effective than the other in improving angiographic outcomes?
October 29, 2008
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Reload With Clopidogrel Before Coronary Angioplasty in Subjects Treated Long Term With Dual Antiplatelet Therapy (RELOAD)
Will increasing the loading dose of clopidogrel in patients already on the therapy further inhibit platelet activity? Is one loading dose better than another for these patients?
October 15, 2008
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Historical Reflection/Stents -- Biodegradable Stents
We now have more data on the use of biodegradable stents. What lessons have we learned and what influence will the data have on the development of next generation devices?
October 14, 2008
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The Occluded Artery Trial (OAT): Nuclear Substudy
Perhaps the lesson from OAT is not that late PCI is pointless, but rather that viability imaging is necessary for patient selection. Does the OAT nuclear substudy support this hypothesis?
October 13, 2008
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Controversies in Lipid Management
Inflammatory markers and their relationship to low-density lipoprotein cholesterol are discussed to explore the current and future boundaries of lipid lowering therapies.
September 15, 2008
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Trial of Routine Angioplasty and Stenting After Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI)
STEMI patients who present to facilities that do not perform PCI are at a disadvantage. TRANSFER-AMI data are reviewed with expert opinion on the clinical and policy implications.
September 12, 2008
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Nicotinic Acid -- The New Old Wonder Drug
Nicotinic acid's mechanism of action and combination therapy efficacy are reviewed along with expert opinion regarding questions about increased insulin resistance.
September 11, 2008
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Bivalirudin Versus Unfractionated Heparin During Percutaneous Coronary Intervention (ISAR-REACT 3)
Is bivalirudin superior to unfractionated heparin in reducing bleeding and ischemia in troponin-negative patients undergoing PCI, after clopidogrel pretreatment? ISAR-REACT 3 results are reviewed.
September 04, 2008
