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Determining the correct dosage for chemotherapeutic agents presents a challenge because there is a fine balance between doses that cause significant drug toxicity and loss of efficacy.
Venous thromboembolism (VTE) is a major cause of morbidity and mortality in patients with cancer. Authors discuss the optimal duration of anticoagulant therapy, treatment of recurrent VTE and more.
This review summarizes why there may not be a universally applicable dose for capecitabine because of interpatient differences in basic physiology, pharmacogenomics and diet.
Metastatic squamous cell carcinoma of the head and neck carries a poor prognosis, but does cetuximab offer clinical benefits beyond those of platinum-based therapies?
Authors discuss management strategies for cardiovascular disease in patients with cancer, focusing on the prevention and treatment of congestive heart failure and myocardial infarction.
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Nature Clinical Practice Oncology
provides oncologists with authoritative and timely interpretations of key developments in the field, translating the latest findings into clinical practice.