Current opinion in drug discovery & development

Table of Contents

2005 - 8 (1)

• High-resolution NMR for metabomics. 

  January 01, 2005

  • [ MEDLINE Abstract ]

• Emerging applications of kinetic biomarkers in preclinical and clinical drug development. 

  January 01, 2005

  • [ MEDLINE Abstract ]

• Approaches to the analysis of cell signaling networks and their application in drug discovery. 

  January 01, 2005

  • [ MEDLINE Abstract ]

• In vivo zebrafish assays for toxicity testing. 

  January 01, 2005

  • [ MEDLINE Abstract ]

• Drug delivery and in vitro models of the blood-brain barrier. 

  January 01, 2005

  • [ MEDLINE Abstract ]

• In vitro ADME phenotyping in drug discovery: current challenges and future solutions. 

  January 01, 2005

  • [ MEDLINE Abstract ]

• Prediction of pharmacokinetics and drug-drug interactions from in vitro metabolism data. 

  January 01, 2005

  • [ MEDLINE Abstract ]

• Idiosyncratic toxicity: mechanistic insights gained from analysis of prior compounds. 

  January 01, 2005

  • [ MEDLINE Abstract ]

• Predicting drug-drug interactions in drug discovery: where are we now and where are we going? 

  January 01, 2005

  • [ MEDLINE Abstract ]

• Minimizing the potential for metabolic activation as an integral part of drug design. 

  January 01, 2005

  • [ MEDLINE Abstract ]

• Immunological mechanisms of drug-induced liver injury. 

  January 01, 2005

  • [ MEDLINE Abstract ]

• Recent uses of topological indices in the development of in silico ADMET models. 

  January 01, 2005

  • [ MEDLINE Abstract ]

• In silico predictive toxicology: the state-of-the-art and strategies to predict human health effects. 

  January 01, 2005

  • [ MEDLINE Abstract ]

• Editorial overview: safety/toxicity threshold concepts in drug discovery and development. 

  January 01, 2005

  • [ MEDLINE Abstract ]