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Antinuclear Antibodies: Marker of Diagnosis and Evolution in Autoimmune Diseases
Review the use and interpretation of antinuclear antibodies as diagnostic markers for autoimmune diseases in this primer.
October 03, 2018
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Critically Elevated Potassium in a 55-Year-Old Female With Chronic Lymphocytic Leukemia
A misdiagnosis as to the cause of hyperkalemia in this patient led to unnecessary dialysis, demonstrating the need to be alert to potentially false potassium results in patients with elevated WBC counts.
September 19, 2018
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Comparison Between a Manual Squamous Cell Carcinoma Antigen Assay and an Automated Assay in a Clinical Setting
Does the automated Elecsys SCC assay provide comparable performance to a manual assay for determining squamous cell carcinoma antigen levels?
September 05, 2018
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Diagnostic Value of Serum SMP30 and Anti-SMP30 Antibody in Hepatocellular Carcinoma
This study evaluated the utility of anti-SMP30 antibody as a new serological marker for diagnosis of hepatocellular carcinoma.
August 22, 2018
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Changing Practice Patterns for Cytotechnologists
How have specific job tasks changed for practicing cytotechnologists in recent years?
August 08, 2018
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What's a Lab to Do During and After a Hurricane?
Is your lab prepared to effectively function during a hurricane or other natural disaster? This article reviews precautions and mitigating actions to take during and after these disruptive events.
July 25, 2018
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Vitamin D Toxicity: A 16-Year Retrospective Study at an Academic Medical Center
The rise in interest in vitamin D supplementation has increased the potential for vitamin D toxicity. How common are toxic effects, at what dosage do they occur, and what are the symptoms?
July 11, 2018
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Spurious Thrombocytopenia in Automated Platelet Count
This article underscores the need for healthcare professionals to be aware of the possibility of spurious data from automated PLT counts. What factors might contribute to these false results?
June 27, 2018
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Assessment of Circulating Tumor Cells as a Predictive Biomarker of Histology in Women With Suspected Ovarian Cancer
Might circulating tumor cells be useful as a diagnostic biomarker in women with complex pelvic masses?
June 13, 2018
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Cervical Cancer Markers: Epigenetics and microRNAs
This review explores the alteration of miRNA expression as a potential early biomarker of cervical cancer.
May 30, 2018
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Enzymatic Functional Assays of Coagulation Using Small Sample Volumes
Is thrombophilia panel testing using a small plasma volume and a digital microfluidic platform as accurate as current methods which require large blood volumes and long turn-around times?
March 12, 2018
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Pharmacogenetics-Based Warfarin Dosing in Patients With Cardiac Valve Replacement
This study identifies genetic polymorphisms which might be helpful for adjusting warfarin dosage to an effective and safe level in patients with cardiac valve replacement.
February 12, 2018
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Clinical and Antibiotic Management of Urinary Tract Infections Pre- and Postimplementation of the CLINITEK AUWi System From Siemens to Screen Out Negative Urine Samples Submitted for Culture
Might screening for suspected UTIs using the CLINITEK AUWi System reduce unnecessary administration of antibiotics?
January 11, 2018
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Opioid Use Disorders, Medication-Assisted Treatment, and the Role of the Laboratory
This review focuses on considerations surrounding urine drug testing, examining the role of both presumptive and definitive testing methods.
December 28, 2017
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Impact of Fasting on Complete Blood Count Assayed in Capillary Blood Samples
Recommendations for fasting before a complete blood count are inconsistent. Does food consumption impact CBC results?
December 26, 2017
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The Clinical Utility of Measuring IgG Subclass Immunoglobulins During Immunological Investigation for Suspected Primary Antibody Deficiencies
In what clinical situations is IgG subclass measurement a useful tool?
December 20, 2017
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Coagulation Testing in the Core Laboratory
This article presents a primer on the mechanisms involved in hemostasis and coagulation pathways, highlighting various methods of coagulation testing and special coagulation studies.
December 18, 2017
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Underestimation of Low Density Lipoprotein-Cholesterol With the Friedewald Equation Versus a Direct Homogenous Low Density Lipoprotein-Cholesterol Assay
Given that the Friedewald equation has been shown to underestimate LDL-C concentrations, what method should be used to accurately ascertain LDL-C levels?
December 13, 2017
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SurePath Specimens Versus ThinPrep Specimen Types on the COBAS 4800 Platform
This study compared two different methodologies of cytologic preparation of cervical specimens for HPV screening. Which method more accurately identified HPV infection?
December 11, 2017
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Variable Potassium Concentrations: Which Is Right and Which Is Wrong?
This case highlights the difficulty in distinguishing between hyperkalemia in a setting of possible tumor lysis syndrome and reverse pseudohyperkalemia. How should the correct etiology be determined?
December 06, 2017
