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Detection of Circulating Antibodies to p16 Protein-Derived Peptides in Hepatocellular Carcinoma
This study suggests that circulating IgG antibodies to p16 protein might be a useful biomarker for hepatocellular carcinoma prognosis assessment as well as early HCC diagnosis.
April 21, 2021
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A Rapid and Accurate Detection Approach for Multidrug-Resistant Tuberculosis Based on PCR-ELISA Microplate Hybridization Assay
The authors developed a PCR-microplate hybridization assay for rapid and accurate detection of mutations responsible for resistance to TB therapeutics and prediction of drug susceptibility.
March 31, 2021
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Plasma Sarcosine Measured by Gas Chromatography-Mass Spectrometry Distinguishes Prostatic Intraepithelial Neoplasia and Prostate Cancer From Benign Prostate Hyperplasia
This study assessed the diagnostic performance of plasma sarcosine as a complementary biomarker to PSA. How well does it distinguish malignancy from benign prostatic hyperplasia?
March 10, 2021
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Types of Assays for SARS-CoV-2 Testing: A Review
This article presents an overview of the molecular and serological tests available for diagnosing COVID-19 as well as ascertaining exposure history and immune status.
February 17, 2021
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14-3-3n Protein in Rheumatoid Arthritis: Promising Diagnostic Marker and Independent Risk Factor for Osteoporosis
This study evaluated the diagnostic value of serum 14-3-3n protein levels in patients with rheumatoid arthritis. Is there an association of this biomarker with osteoporosis in patients with RA?
January 27, 2021
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Clinical Usefulness of Hematologic Indices as Predictive Parameters for Systemic Lupus Erythematosus
This study investigated whether hematologic indices such as NLR, PLR, MPV, PDW, and RDW might serve as markers of disease activity in systemic lupus erythematosus.
January 06, 2021
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Quantitation of Cell-Derived Microparticles in Blood Products and Its Potential Applications in Transfusion Laboratories
Should blood products be routinely screened for cell-derived microparticles? This article discusses how such data could be utilized in transfusion labs to improve outcomes and minimize complications.
December 16, 2020
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Flow Cytometry in the Differential Diagnosis of CD10-Positive Nodal Lymphomas
How can flow cytometry be used for differentiating between between follicular lymphoma and diffuse large B-cell lymphoma/high-grade B-cell lymphoma?
November 25, 2020
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Clinical Use of kappa Free Light Chains Index as a Screening Test for Multiple Sclerosis
This study assessed the diagnostic accuracy of the kappa free light chain index, combined with oligoclonal bands detection, in evaluating patients with suspected MS.
November 04, 2020
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Serum and Saliva Concentrations of Biochemical Parameters in Men With Prostate Cancer and Benign Prostate Hyperplasia
This study evaluated biomarkers in saliva which might potentially be useful for noninvasive screening for early detection of prostate cancer.
October 21, 2020
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STAT5: From Pathogenesis Mechanism to Therapeutic Approach in Acute Leukemia
How might our understanding of STAT5-related signaling pathways contribute to better treatments for T-ALL, such as targeted therapy rather than chemotherapy?
October 14, 2020
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Grossing Technology Today and Tomorrow
This article highlights current challenges in grossing technology and possible future developments. How can grossing technology contribute to modern histology laboratory practice?
September 23, 2020
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The Study of SALL4 Gene and BMI-1 Gene Expression in Acute Myeloid Leukemia Patients
Might SALL4 and BMI-1 be significant prognostic factors and potential therapeutic targets in acute myeloid leukemia?
September 02, 2020
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Association Between Small Dense Low-density Lipoproteins and High-density Phospolipid Content in Patients With Coronary Artery Disease With or Without Diabetes
This study evaluated the phospholipid profile in total plasma, non-HDL, and HDL fractions in patients who had coronary artery disease, with and without type 2 diabetes mellitus.
August 12, 2020
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Safety Considerations in the Laboratory Testing of Specimens Suspected or Known to Contain the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
Review the laboratory biosafety practices necessary to safely process clinical specimens suspected to contain SARS-CoV-2.
July 01, 2020
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Paradoxical Hypercholesterolemia in an Otherwise Healthy Adult Man
With familial hypercholesterolemia ruled out, what was the cause of this 23-year-old patient's hyperlipidemic state?
June 10, 2020
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Low S-adenosylmethionine/ S-adenosylhomocysteine Ratio in Urine is Associated With Chronic Kidney Disease
Are homocysteine, cysteine, S-adenosylmethionine, and S-adenosylhomocysteine levels in urine specimens useful as indicators of renal dysfunction?
May 27, 2020
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Persistent Rivaroxaban Effect Due to Impaired Renal Clearance and Medication Effects
This case highlights the importance of assessing the renal function of and medication list for a patient before starting DOACs such as rivaroxaban.
May 20, 2020
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Expression of Blood Cells Associated CD Markers and Cardiovascular Diseases
Do abnormalities in the expression of the cluster of differentiation markers of blood cells have a prognostic value for cardiovascular diseases?
April 29, 2020
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Clinical Application of Metabolomics in Pancreatic Diseases
Can metabolomics provide a more efficient and sensitive diagnostic method for pancreatic disease? This review explores the potential of metabolomics in early detection, diagnosis, and identification.
April 08, 2020
