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Low S-adenosylmethionine/ S-adenosylhomocysteine Ratio in Urine is Associated With Chronic Kidney Disease
Are homocysteine, cysteine, S-adenosylmethionine, and S-adenosylhomocysteine levels in urine specimens useful as indicators of renal dysfunction?
May 27, 2020
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Quantum Dots-Based Point-of-Care Measurement of Procalcitonin in Finger-Prick Blood and Venous Whole Blood Specimens
This study evaluated the accuracy and sensitivity of a new quantum dots-based POCT device which measures the concentration of procalcitonin in plasma, venous whole blood, and finger-prick blood.
May 06, 2020
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Increased Oxidized High-Density Lipoprotein/High-Density Lipoprotein-Cholesterol Ratio as a Potential Indicator of Disturbed Metabolic Health in Overweight and Obese Individuals
This study evaluated the qualitative characteristics of HDL particles in metabolically healthy and unhealthy overweight and obese subjects. Is the OxHDL/HDL-C ratio useful to assess metabolic health?
April 15, 2020
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Non-High-Density Lipoprotein Cholesterol and Guidelines for Cholesterol Lowering in Recent History
This comprehensive review discusses the history and rationale behind the utility of non-high-density lipoprotein cholesterol as an equivalent target to LDLC for patients in all risk groups.
March 25, 2020
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Cutoff Value for Correcting White Blood Cell Count for Nucleated Red Blood Cells
Commonly used cutoff values for white blood cell count correction can vary widely. Is it time for more standardized thresholds?
March 04, 2020
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A Case of Chronic Thrombocytopenia in a 17-Year-Old Female
A case of gray platelet syndrome, a rare type of thrombocytopenia, is discussed. How is this disorder diagnosed and treated?
February 12, 2020
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Serum S100A8/A9 as a Potentially Sensitive Biomarker for Inflammatory Bowel Disease
Are serum S100A8/A9 measurements a sensitive marker for inflammatory bowel disease? How does it compare with other inflammatory biomarkers?
January 22, 2020
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Demystifying Biclonal Gammopathy
What have we learned about the laboratory characteristics of biclonal gammopathies? Find out what there is to know.
January 01, 2020
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MicroRNA-221 and MicroRNA-222 in Common Human Cancers
A better understanding of the function of microRNAs in various types of cancers could have important implications for cancer treatment.
December 11, 2019
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Prognostic Significance of CHEK2 Mutation in Progression of Breast Cancer
Might detection of mutations in CHEK2 be useful as a prognostic factor for patient response to treatment or potential for metastasis in breast cancer?
November 13, 2019
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Case Report and Literature Review of Nodular Hiradenoma, a Rare Adnexal Tumor That Mimics Breast Carcinoma, in a 20-Year-Old Woman
This case report summarizes the clinical, pathological, and immunohistochemical characteristics of a breast hidradenoma, an uncommon skin adnexal tumor arising from the eccrine or apocrine glands.
October 14, 2019
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Neutrophil-to-Monocyte-Plus-Lymphocyte Ratio as a Potential Marker for Discriminating Pulmonary Tuberculosis from Nontuberculosis Infectious Lung Diseases
The neutrophil-to-lymphocyte ratio has been reported as a useful marker for differentiating between TB and non-TB lung disease. Might the neutrophil-to-monocyte-plus-lymphocyte ratio be even better?
September 13, 2019
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Mean Platelet Volume, Platelet Distribution Width, and Platelet Count, in Connection With Immune Thrombocytopenic Purpura and Essential Thrombocytopenia
This study analyzed and compared MPV and PDW values in immune thrombocytopenic purpura and essential thrombocythemia. How do they compare with values in healthy individuals?
August 27, 2019
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Detection Rate of Colorectal Cancer or Precancer Adenoma by Colonoscopy After 1, 2, or 3 Positive Results via Fecal Immunochemical Testing
Does reducing fecal immunochemical testing pre-screening from 3 vials to a single vial negatively impact CRC or precursor adenoma detection rate?
August 13, 2019
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Improving Laboratory Processes With Total Laboratory Automation
This paper details one medical center's experience with implementation of a total laboratory automation system. Was it effective in optimizing laboratory processes and increasing efficiency?
June 13, 2019
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PIFA PLUSS P4 Assay for Screening of Heparin-Induced Thrombocytopenia
This study evaluated the usefulness of an alternative assay, the PIFA PLUSS P4, as a rapid screening test for the diagnosis of heparin-induced thrombocytopenia.
May 13, 2019
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What Does It Mean for a Recommendation to Be Evidence-Based?
There are many systems for producing evidence-based recommendations--resulting in some confusion over the term. How should we define evidence-based recommendations, and how do we arrive at them?
March 13, 2019
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Marburgviruses: An Update
This review focuses on the most recent developments regarding the highly lethal marburgviruses, including how these viruses are maintained in nature and potential mechanisms of human exposure.
March 12, 2019
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Differential Diagnosis of a Patient With Lysosomal Acid Lipase Deficiency
Was this obese 12-year-old boy's abnormal lipid profile and elevated liver enzymes due to NAFLD or something more unusual?
January 22, 2019
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A Systematic Overview of Zoonotic Helminth Infections in North America
Review diagnosis and characteristics of the 30 most common zoonotic helminth infections that might be encountered in clinical practice in North America.
January 02, 2019
