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ESC 2018Extended Ticagrelor Monotherapy After Stenting Misses Endpoint A novel antiplatelet regimen of extended ticagrelor monotherapy with aspirin added just for the first month after stenting narrowly failed to show superiority over standard treatment in the GLOBAL LEADERS trial.
Medscape Medical News, August 27, 2018
ESC 2018ATTR-ACT: Tafamidis Reduces Mortality in Amyloid CardiomyopathyA drug that binds transthyretin reduced all-cause mortality and cardiovascular hospitalizations and slowed decline in functional capacity in patients with transthyretin amyloid cardiomyopathy.
Top News From ESC 2018: SlideshowHeadlines from the world's largest cardiology meeting include surprising negative trials of fish oil supplements and aspirin
for cardiovascular prevention.
Interviewer: John M. Mandrola, MD; Interviewee: J. Michael Gaziano, MD, MPH
Bloggers From the Floor
Don't Ignore the Many Lessons of the MitraClip FailureReflecting on the MITRA-FR trial, Dr John Mandrola says it can help us learn both specific lessons about the treatment of
people with heart failure and more general lessons on the acceptance of untested therapeutics.
Ten Things I Learned About Aspirin at ESCTwo neutral trials inform an everyday clinical question: who should take aspirin for primary prevention of cardiovascular
disease. John Mandrola spoke with both investigators; these are his takeaways.
Mandrola's ESC 2018 PreviewFrom aspirin to VTE, John Mandrola reflects on the potpourri of relevant data for the practicing clinician at this year's
European Society of Cardiology Congress.
Do Cardiologists Care About CV Prevention?Everyone agrees that prevention is better than cure. However, few ESC attendees joined Melissa Walton-Shirley for the session
on CVD prevention, preferring to stand in line to hear the latest hotlines.
Cardiology 2028: Predicting the FutureMelissa Walton-Shirley attended a session at the European Society of Cardiology Congress titled "Cardiology 10 Years From
Now" and heard some realistic predictions.
What's Driving Physician Burnout in 2018?At a session on burnout at the ESC meeting in Munich, Dr Walton-Shirley heard a first-hand account of a cardiologist who had
a breakdown. The panelists left her hopeful that things will improve.
CANTOS: Anti-Inflammatory Drug Cuts CV Events, CancerThe monoclonal antibody canakinumab cut CV events without affecting cholesterol, providing some with evidence of a new era
in atherosclerotic disease management.
COMPASS: Rivaroxaban Success in Secondary CV PreventionThe combination of a low dose of the factor Xa inhibitor rivaroxaban in combination with aspirin was associated with a reduction
in ischemic events and mortality and a superior net clinical benefit, balancing the bleeding risk in patients with stable
atherosclerotic disease.