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Digoxin for HF Ups Rehospitalizations, Survival Not AffectedA 19th century drug's role in treating HF is still debated in the 21st century: more data links digoxin to increased rehospitalizations.
Is it because many patients have serum levels that are too high?
Medscape Medical News, Sep 19, 2016
Hypotension No Reason to Avoid Sacubitril/Valsartan: PARADIGM-HFAlthough cited as one barrier to embracing the drug for HF, hypotension per se in the sacubitril/valsartan run-in didn't keep
it from besting ACE inhibitors after randomization, researchers say.
Medscape Medical News, Sep 20, 2016
Tolvaptan in Acute HF: Abandon, or Explore Targeted Therapy?There are calls to give up on vasopressin-2 antagonists for acute decompensated heart failure, but some point to possible
subgroup benefits or biomarker-guided therapy as worth pursuing in further trials.
