From theheart.org on Medscape

Coverage from the

European Society of Cardiology (ESC) Congress 2017

August 26 - 30, 2017; Barcelona, Spain

August 26 - 30, 2017 Barcelona, Spain

ESC PURE Shakes Up Nutritional Field: Finds High Fat Intake Beneficial The new study of dietary habits in 135,000 people around the world found that high fat intake, including saturated fat, was associated with a reduced risk of mortality
Medscape Medical News, August 29, 2017
ESC CANTOS: Anti-Inflammatory Drug Cuts CV Events, Cancer The monoclonal antibody canakinumab cut CV events without affecting cholesterol, providing some with evidence of a new era in atherosclerotic disease management.
Medscape Medical News, August 27, 2017
ESC COMPASS: Rivaroxaban Success in Secondary CV Prevention The combination of a low dose of the factor Xa inhibitor rivaroxaban in combination with aspirin was associated with a reduction in ischemic events and mortality and a superior net clinical benefit, balancing the bleeding risk in patients with stable atherosclerotic disease.
Medscape Medical News, August 27, 2017

Meeting Highlights At A Glance

Top News From ESC 2017: Slideshow Headlines from the world’s largest cardiology meeting include a novel approach to secondary MI prevention and a diet study that promises to shake up the nutrition field.

Conference News

ESC PCSK9 Inhibitors: No Short-term Diabetes Risk in Meta-analysis
Medscape Medical News, September 29, 2017
ESC Low LDL Target, No Clinical Gain in Non-CAD Diabetes: EMPATHY
Medscape Medical News, September 27, 2017
ESC Data Bolster Dual Antithrombotic Therapy in AF PCI Patients
Medscape Medical News, September 20, 2017
ESC ESC Guideline Update on Dual Antiplatelet Therapy in CAD
Medscape Medical News, September 14, 2017
ESC Fentanyl in the Cath Lab: Routine but Risky?
Medscape Medical News, September 12, 2017
ESC Apixaban Advantage Before AF Cardioversion Hinted: EMANATE
Medscape Medical News, September 12, 2017
ESC New ESC Guideline on Peripheral Arterial Disease
Medscape Medical News, September 11, 2017
ESC New ESC Guideline on Acute ST-Segment Elevation MI
Medscape Medical News, September 11, 2017
ESC MAUDE: Post-TAVR Leaflet Thrombosis Not Benign
Medscape Medical News, September 8, 2017
ESC Platelet Testing Guides Prasugrel-to-Clopidogrel Switch Post-ACS
Medscape Medical News, September 8, 2017
ESC SPRINT: Caution on Aggressive BP Reduction in Certain Groups
Medscape Medical News, September 7, 2017
ESC Olive-Oil-Enriched Dark Chocolate May Improve Endothelial Function
Medscape Medical News, September 7, 2017
ESC Routine LAA Closure at Heart Surgery: Support From LAACS
Medscape Medical News, September 6, 2017
ESC New Lipid Hypothesis Suggests CETP Inhibitors Better Without Statins
Medscape Medical News, September 6, 2017
ESC Ibuprofen Ups Systolic BP, New-Onset Hypertension Risk
Medscape Medical News, September 6, 2017
ESC STEMI Survival Gains Seen After Early Aldosterone Inhibition
Medscape Medical News, September 1, 2017
ESC Nonagenarians 'Good Candidates' for TAVI Surgery
Medscape Medical News, September 1, 2017
ESC 'Triple' Screening for AAA, PAD, High BP Reduces Mortality
Medscape Medical News, August 31, 2017
ESC BIOFLOW-V: Orsiro Bests Workhorse Xience at 12 Months
Medscape Medical News, August 31, 2017

ESC Remote AF Screening by Patients Boosts Detection: REHEARSE-AF
Medscape Medical News, August 31, 2017
ESC No Gain With Upstream P2Y12 Inhibitors in STEMI PCI
Medscape Medical News, August 30, 2017
ESC Ticagrelor for DAPT Again Questioned in Modern-Era PCI for ACS
Medscape Medical News, August 30, 2017
ESC PURE Shakes Up Nutritional Field: Finds High Fat Intake Beneficial
Medscape Medical News, August 29, 2017
ESC CASTLE-AF: Ablation Reduces Mortality in LV Dysfunction, AF
Medscape Medical News, August 29, 2017
ESC ESC Rapid Rule-In, Rule-Out Algorithm for NSTEMI Safe, Accurate
Medscape Medical News, August 29, 2017
ESC SPYRAL HTN-OFF MED: Reopens Renal-Denervation Conversation
Medscape Medical News, August 29, 2017
ESC Web-Savvy Doctor, Patient Education Efforts Boost OAC Use in AF
Medscape Medical News, August 29, 2017
ESC Anacetrapib REVEALs 'Modest' Effect on Cardiovascular Outcomes
Medscape Medical News, August 29, 2017
ESC Sildenafil Warning in Pulmonary Hypertension After Valve Surgery
Medscape Medical News, August 28, 2017
ESC High Salt Intake Linked to Increased Heart-Failure Risk
Medscape Medical News, August 28, 2017
ESC DETO2X-AMI: No Mortality Benefit of Supplemental Oxygen in Acute MI
Medscape Medical News, August 28, 2017
ESC Broad AF Risk-Factor Intervention Preserves Sinus Rhythm: RACE-3
Medscape Medical News, August 28, 2017
ESC Underweight Patients Fare Worse After Heart Catheterization
Medscape Medical News, August 27, 2017
ESC COMPASS: Rivaroxaban Reduces CV and Limb Events in PAD
Medscape Medical News, August 27, 2017
ESC Gender Gap Reduced for Post-AMI In-Hospital Mortality
Medscape Medical News, August 27, 2017
ESC CANTOS: Anti-Inflammatory Drug Cuts CV Events, Cancer
Medscape Medical News, August 27, 2017
ESC COMPASS: Rivaroxaban Success in Secondary CV Prevention
Medscape Medical News, August 27, 2017
ESC Barcelona, Still Healing, Welcomes ESC Congress
Medscape Medical News, August 21, 2017

Popular News from ESC 2016

Primary Prevention ICDs Still Right for Non-CAD HF? DANISH Says No UPDATED // A major trial finds that with contemporary heart-failure therapies, primary-prevention defibrillators may not be the life-savers they used to be in nonischemic HF. But is the story that simple?
Medscape Medical News, Aug 28, 2016
SAVE: No CV Event Reduction With CPAP in Patients With CVD UPDATED // A randomized trial shows no reduction in cardiovascular events in patients with established coronary or cerebrovascular disease and obstructive sleep apnea from CPAP therapy.
Medscape Medical News, Aug 28, 2016
Factor Xa 'Antidote' Shows Rapid Effect in Preliminary Results Amid an FDA request for more data before it will consider approval, the ANNEXA-4 trial proceeds, with preliminary results showing rapid, effective benefit from andexanet alfa in countering acute bleeding in patients on factor Xa inhibitors.
Medscape Medical News, Aug 30, 2016

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Perspectives from ESC

Heart Failure and AF: Where Does Ablation Fit in?
Ileana L. Piña, MD, MPH; Luigi Di Biase, MD, PhD
CASTLE-AF: Ablate Patients With HF Before It's too Late?
John M. Mandrola, MD; Nassir F. Marrouche, MD
ESC 2017: Updates in Antithrombotic Strategies
Sanjit S. Jolly, MD, MSc, FRCPC; Christopher B. Granger, MD
Halting HF in Patients With Diabetes: Insights From EMPA-REG
Ileana L. Piña, MD, MPH; Javed Butler, MD, MPH, MBA
Lipid-Lowering, CV Effects of Anacetrapib REVEALed
John M. Mandrola, MD; Martin J. Landray, MB ChB, PhD, FRCP
ESC 2017: Lipids and Prevention Takeaways
Sanjit S. Jolly, MD, MSc, FRCPC; Christopher B. Granger, MD; Eva Prescott, MD, DMSC
Sanjay Kaul Grades Four Big Trials From ESC 2017
Sanjay Kaul, MD
CANTOS: Future Promise for Targeting Inflammation in CVD
Clyde W. Yancy, MD, MSc; Robert A. Byrne, MB BCh, PhD
CANTOS: Lowering Inflammation, Not LDL-C, to Reduce CVD
John M. Mandrola, MD; Paul M. Ridker, MD

Bloggers from the Floor

FOURIER: Post Hoc Analysis Doesn't Move the Needle Yes, PCSK9 inhibitors can drop LDL-C levels very, very low, but Dr John Mandrola is not yet convinced of their viability in the real world after the presentation of a FOURIER study at ESC 2017.
The COMPASS Trial: Time for Clear Heads, Not Celebration Dr John Mandrola is not convinced that the COMPASS trial findings warrant adding low-dose of rivaroxaban twice daily on top of aspirin to an already pill-burdened patient population.
CASTLE-AF: Does It Change the World of AF Ablation? Dr John Mandrola discusses the CASTLE-AF trial, the reaction from the EP community, and some of his concerns.
Quick Thoughts on the CANTOS Trial Quick Thoughts on the CANTOS Trial Dr John Mandrola offers his first reactions to the landmark CANTOS trial presentation at the ESC meeting.
Women and Heart Disease: A Different Animal Dr Melissa Walton-Shirley recounts a presentation by Dr Noel Bairey Merz on clinics dedicated to women and MI without obstructive coronary artery disease, heart failure with preserved ejection fraction, and adverse pregnancy outcomes.
How One Morning at ESC 2017 Might Change Your Practice Dr Melissa Walton-Shirley highlights some standout results and some that she felt were less than illuminating on the first few days of ESC 2017.
ESC 2017: No Tinc Por (I'm Not Afraid) Dr Melissa Walton-Shirley visits the memorial to terrorist victims in Barcelona and reflects on the changes in the world.

Preview Commentary

Mandrola's ESC 2017 Preview: Some Truly 'Hot' Hotlines
John Mandrola, MD
CANTOS: Dousing the Fire Within to Reduce CVD
Michelle L. O'Donoghue, MD, MPH

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