Man With COVID Finally Tests Negative After 411 Days

Ralph Ellis

November 04, 2022

Editor's note: Find the latest COVID-19 news and guidance in Medscape's Coronavirus Resource Center.

A man in England who was infected with an early strain of COVID-19 was finally cleared 411 days after first testing positive, according to experts in the United Kingdom. 

The man was treated with a mixture of neutralizing monoclonal antibodies, King's College London said in a news release. 

The man, 59, tested positive in December 2020 and tested negative in January 2022. He had a weakened immune system because of a previous kidney transplant. He received three doses of vaccine and his symptoms lessened, but he kept testing positive for COVID.

To find out if the man had a persistent infection or had been infected several times, doctors did a genetic analysis of the virus.

"This revealed that the patient’s infection was a persistent infection with an early COVID variant — a variation of the original Wuhan variant that was dominant in the U.K. in the later months of 2020. Analysis found the patient’s virus had multiple mutations since he was first infected," King's College said.


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