Evaluation of a Novel Optical Smartphone Blood Pressure Application

A Method Comparison Study Against Invasive Arterial Blood Pressure Monitoring in Intensive Care Unit Patients

Olivier Desebbe; Chbabou Anas; Brenton Alexander; Karim Kouz; Jean-Francois Knebel; Patrick Schoettker; Jacques Creteur; Jean-Louis Vincent; Alexandre Joosten


BMC Anesthesiol. 2022;22(259) 

In This Article


Arterial hypertension is a leading predicting factor of poor health outcome worldwide, in both developed and developing countries.[1–3] In 2020, just over 1.4 billion adults had hypertension, but it is estimated that only 46% of people with arterial hypertension are aware of having the disease.[4] Arterial hypertension and its complications (e.g., kidney failure, stroke and heart failure) are responsible for significant resource use across healthcare systems worldwide. Arterial hypertension is most commonly diagnosed using automatic ambulatory non-invasive blood pressure (BP) measurements, with oscillometry and a pressure cuff around the arm or wrist being the most frequently used method. Healthcare systems in most developed countries encourage self-measurement of BP at home for a wide variety of reasons, such as enabling more frequent measurements, eliminating the white coat effect, detecting masked arterial hypertension, and facilitating better titration of treatment changes by the physician, which may ultimately reduce cardiovascular complications.[5–7]

The technological capabilities of our "smartphones" have evolved dramatically in recent years, which has led to the emergence of multiple health applications that can be used in the diagnosis, prevention, and management of several diseases.[8,9] Newer mobile phone applications are now able to numerous vital signs non-invasively[10,11] and even display flow variables or dynamic parameters of fluid responsiveness.[12–15] As such, having such smartphone application widely available may one day improve the management of arterial hypertension without the current bulky and costly devices. Considering that at least 6.6 billion people own a smartphone worldwide, an accurate and reliable method to measure BP using a smartphone would enable a large percentage of the world's population to have easy access to arterial hypertension screening and monitoring.

A new optical smartphone application for BP measurement (OptiBP™) has recently been developed by Biospectal (Lausanne, Switzerland) and tested against upper arm cuff oscillometry,[16–19] but no studies have compared OptiBP™-derived BP values with invasive BP values obtained using an arterial catheter as the reference method. We therefore conducted an observational study in intensive care unit (ICU) patients to compare BP values obtained with the OptiBP™ with those obtained invasively using an arterial catheter.