Postoperative But Not Preoperative Depression Is Associated With Cognitive Impairment After Cardiac Surgery

Exploratory Analysis of Data From a Randomized Trial

Choy Lewis; Mehmet E. Dokucu; Charles H. Brown; Lauren Balmert; Nina Srdanovic; Ashwin Shaan Madhan; Sahej Singh Samra; John Csernansky; Jordan Grafman; Charles W. Hogue


BMC Anesthesiol. 2022;22(157) 

In This Article

Sample Size

Insofar as the present study is a secondary analysis of a prior randomized clinical investigation, the sample size was set based on the parent study. There was no power calculation for the present study. The sample size for the parent study was based on detecting differences in the proportion of patients with a composite adverse neurologic outcome between the usual care and autoregulation groups.