Treatment of Fusarium Osteomyelitis in a Diabetic Foot Ulcer Complicated by Antineoplastic Chemotherapy

Tyson O. Strom, DPM; Rebecca A. Burmeister, DPM, MPH; Gary M. Rothenberg, DPM, CWS; Sari J. Priesand, DPM


Wounds. 2022;34(4):e37-e41. 

In This Article


Fusarium is a rare cause of osteomyelitis. When it presents in a patient who is severely immunocompromised, it can be challenging to determine diagnosis and treatment. The current patient received a diagnosis of DFO while undergoing active antineoplastic chemotherapy treatment. The side effects of the chemotherapy and chronicity of the wound with no response to antimicrobial therapy guided the authors' treatment decision. The patient was treated with a conservative procedure with a bedside partial phalangectomy and antimicrobial medications postprocedure. The patient responded well to the treatment, and the ulceration ultimately healed. This case report may serve as the first to demonstrate successful remission of Fusarium osteomyelitis in a patient of immunocompromised status with a conservative procedure and adjunct antifungal therapy.