One limitation of our study is the small sample size, in that we only examined 30 specimens from patients who were RT-PCR–positive and 30 specimens from patients who were negative. In addition, all our specimens were collected within 21 days of the RT-PCR testing. Larger studies evaluating specimens collected at longer time intervals are needed to assess the utility of serological assays in confirming past SARS-CoV-2 infection and immunity.
ELISA, enzyme-linked immunosorbent assay; RT-PCR, real-time polymerase chain reaction; UMMC, University of Mississippi Medical Center; RBD, receptor binding domain; PBS, phosphate-buffered saline.
Lab Med. 2022;53(3):262-265. © 2022 American Society for Clinical Pathology