Literature Search Strategy and Selection Criteria
Studies were selected from the peer-reviewed literature using NCBI and Google Scholar. We searched the databases using the following keywords: central and peripheral nervous systems, COVID-19, SARS-CoV-2, coronavirus, stroke, encephalopathy, neurocognitive impairment, hypercoagulability, encephalitis, neurologic infection, seizure and neuroinflammation. We also reviewed bibliographies of relevant articles. Non-peer-reviewed studies and single case reports were not included as references unless they were highly informative.
COVID-19 = coronavirus disease 2019; CVST = cerebral venous sinus thrombosis; ICU = intensive care unit; IVIg = intravenous immunoglobulin
The authors thank Brittney Hlavay for creation of figures, Nathalie Arbour for helpful discussions, Rebecca Folkerth, New York University for providing the post-mortem tissue images and Govind Nair for providing the MR images of the brain.
No specific funding was received towards this work.
The authors report no competing interests.
Brain. 2022;144(12):3576-3588. © 2022 Oxford University Press