Cost-Effectiveness of Lipid-Lowering Treatments in Young Adults

Ciaran N. Kohli-Lynch, PHD; Brandon K. Bellows, PHARMD; Yiyi Zhang, PHD; Bonnie Spring, PHD; Dhruv S. Kazi, MD; Mark J. Pletcher, MD; Eric Vittinghoff, PHD; Norrina B. Allen, PHD; Andrew E. Moran, MD


J Am Coll Cardiol. 2021;78(20):1954-1964. 

In This Article


Around one-quarter of U.S. young adults have elevated LDL-C. This mathematical modeling study found that initiating statin treatment in young adults with an LDL-C level of ≥130 mg/dL is highly cost-effective in men and intermediately cost-effective in women.