The Clinical Characteristics of Patients With Pulmonary Hypertension Combined With Obstructive Sleep Apnoea

Lu Yan; Zhihui Zhao; Qing Zhao; Qi Jin; Yi Zhang; Xin Li; Anqi Duan; Qin Luo; Zhihong Liu


BMC Pulm Med. 2021;21(378) 

In This Article


OSA has a high incidence in patients with PH. OSA may aggravate PH to some extent, and advanced age, male sex and lower daytime PaO2 could predict the presence of OSA. It may be important to identify and treat PH patients with OSA. The clinical significance of PH with OSA requires further investigation.


First, because polysomnography is time-consuming and laborious, it is generally not used for preliminary screening. Therefore, portable cardiopulmonary breathing monitoring was used for patient sleep monitoring in this study. Due to the low incidence of PH, too few patients had each disease type for subgroup analysis, and selection bias was inevitable in this prospective study. In addition, we did not follow up the patients, so we could not determine the effect of OSA on the long-term survival of patients with PH. We did not investigate whether PH could be alleviated by the correction of OSA. Large, prospective cohort studies are needed to further explore these issues.