No Vaccine, Thank You: We're Invincible

F. Perry Wilson, MD, MSCE


October 27, 2021

This transcript has been edited for clarity.

Welcome to Impact Factor, your weekly dose of commentary on a new medical study. I'm Dr F. Perry Wilson of the Yale School of Medicine.

With vaccine authorizations hitting the 5- to 12-year-old age group soon, we'll see an uptick in the overall vaccination rate in the United States, but of course there are tens of millions people who are eligible for the vaccine who remain unvaccinated. This is a problem. According to a Kaiser study, 90,000 COVID deaths since June 2021 would have been prevented by vaccination.


But the rhetoric surrounding why people choose not to get vaccinated tends to focus on the perception of harm. The narrative quickly settles on the idea that people who don't get vaccinated think the risks of the vaccine are way higher than they actually are. And of course, plenty of good faith and bad faith debate occurs on social media surrounding those risks.

But that's a bit one-sided. A new article appearing in PLOS One shows us what is, I think, an equally plausible reason some people choose not to get vaccinated. It's not that they overestimate the risk of vaccination; they underestimate the risk of COVID. Or, as the authors put it, they feel invincible.

Invincibility is actually a relatively well-studied phenomenon in the psychological literature. It has various definitions, but it basically refers to an individual, false belief that one will be successful in any endeavor, regardless of risk. Invincibility promotes risky behaviors, including taking less precautions when driving or having sex. Maybe people don't choose to get vaccinated because they feel invincible to coronavirus.

A feeling of invincibility is quite personal; you might even call it egocentric. But we don't only get vaccinated to protect ourselves, but also to protect our community. How does a society's stance on collectivism interplay with the individual feeling of invincibility to lead to choices about vaccination?

To answer the questions, the researchers conducted a survey that spanned 51 countries and nearly 300,000 individuals. Of note, the survey was conducted from July to November 2020 — so no vaccines had actually been released yet. To get at the sense of invincibility they asked, "How serious would it be if you became infected with COVID-19"? They also asked about intention to get vaccinated and about how important it is to take actions to prevent the spread of COVID-19 in your community.


Let's focus on willingness to get vaccinated.


Topline results are no surprise. Those who felt invincible — that an infection would be "not at all serious" — were much more likely to state they weren't going to be vaccinated. In fact, it appears that a feeling of invincibility was the single most significant predictor of not getting vaccinated — beating out age, sex, and level of education.

Feeling invincible to COVID-19 was also linked to feeling that pro-social behaviors, like mask-wearing and social distancing, aren't important — which makes sense I suppose. If you don't think COVID can hurt you, you might also think it can't hurt others.

That said, in countries with more of a collectivist culture, the effect of feeling invincible was strongly mitigated. As you can see here, as the collectivism score of a country increases, the vaccine intention, even among those who feel invincible, also increases.

This suggests a potential path forward, the authors write. Perhaps in the less collectivist countries, like the United States, an appeal to community would move the needle, even among those who feel they would handle the virus just fine.

President Biden has been hitting the pro-social themes in multiple speeches, probably for just this reason.

As President Biden said,

It's the only way we ever get back to normal — to cheer together in stadiums full of fans; to gather together on holidays again safely; go to graduations, weddings.

Of course, sometimes it's the message, and sometimes it's the messenger.

Look, there are plenty of people out there who believe that COVID-19 won't affect them very much. Many of them are right. But some of them are very wrong. And right now, we have no good way to figure out in advance who is who. And that's the problem with feeling invincible, right? In the end, the real end, the ultimate end, none of us are.

F. Perry Wilson, MD, MSCE, is an associate professor of medicine and director of Yale's Clinical and Translational Research Accelerator. His science communication work can be found in the Huffington Post, on NPR, and here on Medscape. He tweets @fperrywilson and hosts a repository of his communication work at

Follow Medscape on Facebook, Twitter, Instagram, and YouTube


Comments on Medscape are moderated and should be professional in tone and on topic. You must declare any conflicts of interest related to your comments and responses. Please see our Commenting Guide for further information. We reserve the right to remove posts at our sole discretion.