Amniotic Membrane Dressing Versus Nitrofurazone-impregnated Dressing in the Treatment of Second-degree Burn Wounds

A Randomized Clinical Trial

Jafar Kazemzadeh, MD; Awat Yousefiazar, MSc; Afshin Zahedi, MD


Wounds. 2021;33(8) 

In This Article


Results of an RCT comparing factors influencing the benefits of using amniotic membrane compared with nitrofurazone dressing in second-degree burn wounds indicated fewer dressing changes, fewer days in hospital, better epithelialization on day 7 of treatment, decreased morphine intake, and less pain severity in patients receiving amniotic membrane treatment. Improved healing and reduced pain suggest an amniotic membrane dressing is a viable choice for second-degree burn wound care. Future research in larger cohorts is warranted.