The Changing Face of Trigeminal Neuralgia

A Narrative Review

Stine Maarbjerg MD, PhD; Rafael Benoliel BDS (Hons)


Headache. 2021;61(6):817-837. 

In This Article

Peripheral Procedures

Local Anesthetics

Nerve blocks may provide some hours of absolute pain relief in CTN, and we have used these to permit patients to participate in important personal activities. Within a hospital setting, continuous infusion of local anesthetic may be feasible but depends on the nerve branches involved.[192]

Peripheral procedures include neurectomy, cryotherapy, and glycerol injection. All have high recurrence and complication rates and give no benefit over ganglion-level procedures. All peripheral procedures aim at inducing nerve damage and carry the risk of developing neuropathic pain. Peripheral procedures should be reserved for emergency use or in patients with significant medical problems that make other procedures unsafe.[193]