The SARS-CoV-2 genome can be detected in biological fluids such as saliva, urine, and semen in a small percentage of sexually active men who have recovered from COVID-19. Even if our evidence suggests that the risk of SARS-CoV-2 sexual transmission after recovery in stable partners seems negligible, caution should be taken when managing the semen of healed COVID-19 patients during assisted reproduction and cryopreservation.
Most importantly, one-quarter of men who recovered from COVID-19 demonstrated oligo-crypto-azoospermia and signs of male genital tract inflammation, strictly related to disease severity. Therefore, our study suggests that COVID-19 patients of reproductive age should undergo a careful follow up for reproductive function and semen parameters.
The data underlying this article will be shared on reasonable request to the corresponding author.
Hum Reprod. 2021;36(6):1520-1529. © 2021 Oxford University Press