Prone Position in Intubated, Mechanically Ventilated Patients With COVID-19

A Multi-Centric Study of More Than 1000 Patients

Thomas Langer; Matteo Brioni; Amedeo Guzzardella; Eleonora Carlesso; Luca Cabrini; Gianpaolo Castelli; Francesca Dalla Corte; Edoardo De Robertis; Martina Favarato; Andrea Forastieri; Clarissa Forlini; Massimo Girardis; Domenico Luca Grieco; Lucia Mirabella; Valentina Noseda; Paola Previtali; Alessandro Protti; Roberto Rona; Francesca Tardini; Tommaso Tonetti; Fabio Zannoni; Massimo Antonelli; Giuseppe Foti; Marco Ranieri; Antonio Pesenti; Roberto Fumagalli; Giacomo Grasselli

Disclosures

Crit Care. 2021;25(128) 

In This Article

Conclusions

During the most intense months of the first wave of 2020 COVID-19 pandemic in Italy, critically ill, intubated and mechanically ventilated patients with ARDS were frequently placed in prone position. The more severe the respiratory failure, the more frequent the use of this rescue therapy. Placing the patients in prone position has the main purpose of reducing the injurious effects of mechanical ventilation. In addition, it is a cheap and effective manoeuvre, able to improve oxygenation in the vast majority of patients with respiratory failure due to COVID-19. In this population, the main mechanisms responsible for the improved oxygenation seems to be the improvement of the ventilation/perfusion matching.

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