Association Between Physical Activity and Mortality in Patients With Claudication

Andrew W. Gardner; Odessa Addison; Leslie I. Katzel; Polly S. Montgomery; Steven J. Prior; Monica C. Serra; John D. Sorkin


Med Sci Sports Exerc. 2021;53(4):732-739. 

In This Article

Conclusions and Clinical Significance

In conclusion, light-intensity physical activity, which may be far below recommended physical activity guidelines, is associated with lower risk of all-cause and cardiovascular mortality by nearly 50% in high-risk patients with PAD and claudication. Furthermore, moderate- to vigorous-intensity physical activity performed regularly, which may approach the recommended guidelines, is associated with 58% and 66% lower risk of all-cause and cardiovascular mortality, respectively. The clinical significance is that most patients with claudication are capable of occasionally engaging in light-intensity physical activity, and the survival benefits associated with light-intensity physical activity make it a compelling behavioral intervention that extends beyond improving ambulation.