Severe Acute Respiratory Syndrome Coronavirus 2-induced Acute Aortic Occlusion

A Case Report

Artem Minalyan; Franklin L. Thelmo; Vincent Chan; Stephanie Tzarnas; Faizan Ahmed

Disclosures

J Med Case Reports. 2021;15(112) 

In This Article

Background

AAO is a very rare life-threatening condition associated with high mortality despite advances in surgical management, with a 30-day mortality rate of 21–52%. Saddle embolus, in situ thrombosis in the setting of severe atherosclerotic disease, and occlusion of previous surgical constructions (for example, stents, grafts) are considered the most common causes of AAO.[1] Abdominal aortic aneurysm (AAA) is another condition that is known to be associated with an increased risk of AAO. It is thought that AAA can cause AAO as there is an interruption in laminar flow leading to turbulence and an increased risk of clot formation.[2] Multiple conditions including malignancies, infections, and connective tissue disorders are known to lead to hypercoagulability. Therefore, patients with said conditions are also at increased risk of thrombotic events.[3] SARS-CoV-2 is the cause of the current 2019–2020 pandemic. There is emerging evidence that it is also associated with hypercoagulable states, therefore, leading to thrombotic events.[4] Arterial thrombotic events have also been described in the literature.[5,6] It is speculated that endovascular damage triggers the cascade of pathologic changes that leads to the development of arterial thrombi.[7]

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