Survival Benefit and Toxicity Profile of Adjuvant Icotinib for Patients With EGFR Mutation-Positive Non-Small Cell Lung Carcinoma

A Retrospective Study

Ziqing Zeng; Bo Yan; Yulong Chen; Lianmin Zhang; Jianquan Zhu; Fan Yang; Feng Wei; Terence Chi Chun Tam; Diego Kauffmann-Guerrero; Ross Andrew Soo; Xiubao Ren; Jian You


Transl Lung Cancer Res. 2020;9(6):2401-2410. 

In This Article


This retrospective study suggests that adjuvant icotinib might be associated with a promising survival benefit with an acceptable toxicity profile. The OS rate observed in this study was higher than that reported in the literature for chemotherapy. These results are essential because EGFR-TKIs are considered central to the modern tailored management of resectable NSCLC.