Cost-Utility Analysis of Negative Pressure Wound Therapy Compared With Traditional Wound Care in the Treatment of Diabetic Foot Ulcers in Iran

Vahid Alipour, PhD; Aziz Rezapour, PhD; Mehdi Ebrahimi, MD; Jalal Arabloo, PhD


Wounds. 2021;33(2):50-56. 

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There are some limitations related to this study. First, the study was conducted from the provider's perspective. The authors suggest conducting future studies from a social perspective, which is more complete and considered to be best practice in economic evaluation studies that include all the costs and outcomes associated with a technology. The second limitation is related to the lack of Iranian data on transition probabilities, quality of life, and utility weights. In the present study, the researchers used data from other countries. The lack of locally available outcome (effectiveness) data indicates the need for more study in this arena to provide more accurate local economic evaluations. A third limitation was the 1-year time horizon of the study. Due to the chronic nature of the DFU, longer-term economic modeling would result in a clearer picture when comparing the technologies and their costs. Further, to address the uncertainty related to the Markov model, comprehensive types of sensitivity analyses should be used.[31]