Retinal Imaging Study Diagnoses in COVID-19

A Case Report

José M. Ortiz-Egea; Jorge Ruiz-Medrano; José M. Ruiz-Moreno


J Med Case Reports. 2021;15(15) 

In This Article


Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). In humans, diseases of the coronavirus family range from the mild common cold to more severe diseases such as Middle East respiratory syndrome (MERS) and SARS.[1]

COVID-19 can cause pathological ophthalmologic involvement, including conjunctivitis, chemosis, hyperemia, epiphora, secretion,[2] photophobia, dry eye,[3] neuro-ophthalmic manifestations such as optic neuritis, cranial nerve palsies, nystagmus or visual field defects,[4] and descriptions of retinal aggression.[5,6]

Optical coherence tomography (OCT) has proved to be a useful tool for the in vivo study of the retina, where hyperreflective structures range from normal retina (nerve, fiber layer, inner and outer plexiform layers), nerve fiber layer myelination or vessels, to lesions such as hard exudates, haemorrhages, fibrosis, or focal inflammation, among others. Some of those imply the appearance of a shadow below said structures that may lead to interpretation errors.[7]