Late-onset Myocardial Infarction and Autoimmune Haemolytic Anaemia in a COVID-19 Patient Without Respiratory Symptoms, Concomitant With a Paradoxical Increase in Inflammatory Markers

A Case Report

Maria Chiara Pelle; Bruno Tassone; Marco Ricchio; Maria Mazzitelli; Chiara Davoli; Giada Procopio; Anna Cancelliere; Valentina La Gamba; Elena Lio; Giovanni Matera; Angela Quirino; Giorgio Settimo Barreca; Enrico Maria Trecarichi; Carlo Torti


J Med Case Reports. 2020;14(246) 

In This Article


Although the underlying mechanisms are not well known, we confirm that SARS-CoV-2 infection may trigger AIHA, as well as other complications, such as myocardial infarction, possibly related to cytokine storm and hyperinflammation. This is further supported by the concomitant increase in inflammatory markers such as IL-6 in our patient. Moreover, our case highlights the need for laboratory and clinical surveillance of patients hospitalized for COVID-19 for a prompt diagnosis of late-onset complications, especially when markers such as IL-6 do not return to normal or paradoxically increase during the course of an otherwise benign disease.