Effects of in Vitro Fertilization (IVF) Therapies on Metabolic, Endocrine and Inflammatory Status in IVF-Conceived Pregnancy

Ayla Coussa; Hayder A. Hasan; Thomas M. Barber


Clin Endocrinol. 2020;93(6):705-712. 

In This Article


In vitro fertilization therapy induces weight gain and impairment in glucose, insulin and lipid homeostasis in failed IVF. Improvement of glucose homeostasis, decrease in thyroid profile and increase in lipid profile in clinical pregnancy are likely a pregnancy-related effect. Neither adiponectin nor LBP is affected by IVF therapies and during early IVF-conceived pregnancy. Hence, monitoring of metabolic and endocrine parameters in 3 months following IVF should be implemented in clinical practice, particularly with repeated and failed IVF attempts.