Ischemic Stroke Occurs Less Frequently in Patients With COVID-19

A Multicenter Cross-Sectional Study

Kimon Bekelis, MD; Symeon Missios, MD; Javaad Ahmad, MD; Nicos Labropoulos, PhD; Clemens M. Schirmer, MD, PhD; Daniel R. Calnan, MD, PhD; Jonathan Skinner, PhD; Todd A. MacKenzie, PhD


Stroke. 2020;51(12):3570-3576. 

In This Article


Using a comprehensive all-payer cross-section of patients from a large healthcare system in New York State, we did not identify an increased occurrence of stroke among patients with COVID-19. Patients with stroke with concurrent SARS-CoV-2 infection demonstrated increased case-fatality and discharge to rehabilitation. Our results were robust when considering several observational techniques to account for confounders. The observed associations were paralleled in MI, a disease with similar risk factors and epidemiology to stroke. Although no definitive conclusions can be drawn about the causal relationship between COVID-19 and stroke from our observational study, our report is contributing to an ongoing debate about possible systemic complications of SARS-CoV-2 infection.