The Personality Dispositions and Resting-state Neural Correlates Associated With Aggressive Children

Qingqing Li; Mingyue Xiao; Shiqing Song; Yufei Huang; Ximei Chen; Yong Liu; Hong Chen


Soc Cogn Affect Neurosci. 2020;15(9):1004-1016. 

In This Article


We conducted a detailed investigation of the relevance of personality factors and neuroanatomical factors for aggression in middle children. The behavioral results indicated that aggression is negatively correlated with agreeableness and positively correlated with neuroticism. Moreover, we found multiple brain networks contributing to aggression in children. The fALFF results showed that higher aggression is linked to deactivation in the left temporal lobe, limbic area and parietal lobe, areas functionally related to empathy and social cognition. The rsFC results showed that physical and total aggressions are negatively associated with functional connectivity between the right PHG and the right putamen and that this connectivity moderates the influence of neuroticism on total aggression. The analysis based on sex indicated a possible sex difference in the neurodevelopmental mechanisms underlying aggression in middle childhood. Our findings on the specific dispositional and neurological underpinnings of aggressiveness in children could contribute to enhancing the understanding of maladaptive processes and determining effective aggression prevention and intervention programs.