Retrospective Comparison of Focused Shockwave Therapy and Radial Wave Therapy for Men With Erectile Dysfunction

Shannon S. Wu; Kyle J. Ericson; Daniel A. Shoskes

Disclosures

Transl Androl Urol. 2020;9(5):2122-2128. 

In This Article

Results

Forty-eight men with ED who met our criteria were treated with SWT: 24 men with fSWT and 24 with rWT. The median age of patients was 65.6 (IQR, 51–70), median pre-treatment SHIM 8 (IQR, 5–13), and 85% (41/48) used PDE5i. Table 1 shows the baseline characteristics of each cohort. There was no statistical difference between the fSWT and rWT groups in age (61.3 vs. 60.5 years), duration of ED symptoms (61 vs. 72 months), pre-treatment use of PDE5i (79% vs. 92%), or the baseline SHIM score (9.3±4.2 vs. 9.3±4.8). All patients completed their 6-week treatment course. All patients had pre- and post-treatment SHIM scores and no missing data or loss to follow-up requiring imputation.

At 6 weeks post-treatment, there was a clinically and statistically significant increase in SHIM scores with both modalities (Figure 1). The mean SHIM of patients treated by rWT improved from 9.3 to 16.1 (SD 5.9) (P<0.0001). Similarly, the mean SHIM of patients treated by fSWT improved from 9.3 to 15.5 (SD 5.7) (P<0.001). There was no statistical difference in the delta SHIM between rWT and fSWT (P=0.42; Figure 2).

Figure 1.

Box and whisker plots of pre- and post-treatment Sexual Health Inventory in Men (SHIM) scores for men treated by (A) focused shockwave therapy and (B) radial wave therapy (rWT). X-marks within the box plot denote the mean SHIM score.

Figure 2.

Mean change in Sexual Health Inventory in Men (SHIM) score from pre- to post-treatment with focused shockwave therapy (fSWT) and radial wave therapy (rWT).

Among men treated by rWT, 25% (6/24) reported no improvement (grade 1), 42% (10/24) reported erections sufficient for penetration with the assistance of PDE5i (grade 2), and 33% (8/24) reported sufficient erections without needing PDE5i (grade 3). In the fSWT group, 46% (11/24) reported no improvement (grade 1), 17% (4/24) reported erections sufficient for penetration with the assistance of PDE5i (grade 2), and 37.5% (9/24) reported sufficient erections without needing PDE5i (grade 3). In the rWT group, 75% (18/24) had a ≥ grade 2 response compared to 54% (13/24) in the fSWT group; however, this was not a statistically significant difference (P=0.42).

None of the patients included in this study experienced an adverse event.

Comments

3090D553-9492-4563-8681-AD288FA52ACE

processing....