Does Periodontitis Affect the Treatment Response of Biologics in the Treatment of Rheumatoid Arthritis?

Masahiro Tachibana; Yukio Yonemoto; Koichi Okamura; Takahito Suto; Hideo Sakane; Tetsuya Kaneko; Trang Thuy Dam; Chisa Okura; Tsuyoshi Tajika; Yoshito Tsushima; Hirotaka Chikuda


Arthritis Res Ther. 2020;22(178) 

In This Article


There was a negative correlation between the extent of PD at baseline and the treatment response of RA in patients who received biological therapy. Therefore, the condition of periodontitis might affect ACPA levels and the treatment response of RA. The evaluation of periodontal condition is considered an essential part for the management of RA.