Sporotrichosis in Renal Transplant Patients

Two Case Reports and a Review of the Literature

Mazhar Hussein Amirali; Jacques Liebenberg; Sheylyn Pillay; Johan Nel


J Med Case Reports. 2020;14(79) 

In This Article


Sporotrichosis is a rare opportunistic infection that occurs mostly in renal transplant patients; it can be localized (lympho-cutaneous) or involve various organ systems (disseminated). A high index of suspicion is required to make the diagnosis with the important differential diagnoses kept in mind. A history of trauma through recreational or occupational exposure to the fungus may assist in making a diagnosis. Treatment is difficult, with long-term use of potentially nephrotoxic and Cytochrome P450 3A4 inhibitor antifungal agents, which necessitate stringent monitoring of therapeutic drug levels to counteract CNI toxicity.