Maternal Spontaneous Abortion and the Risk of Attention-deficit/Hyperactivity Disorder in Offspring

A Population-based Cohort Study

Hui Wang; Fei Li; Maohua Miao; Yongfu Yu; Honglei Ji; Hui Liu; Rong Huang; Carsten Obel; Jun Zhang; Jiong Li


Hum Reprod. 2020;35(5):1211-1221. 

In This Article


Our findings suggest that maternal history of SA is associated with an increased rate of ADHD in offspring, and the rate increases with the number of maternal SA. These findings are consistent when taking into consideration of a number of maternal and offspring characteristics, as SA is quite frequent (varying from 15 to 20%) and a small increase of neurodevelopmental problems in offspring could have major public health implications.