Cannabis Use Is Associated With a Small Increase in the Risk of Postoperative Nausea and Vomiting

A Retrospective Machine-learning Causal Analysis

Wendy Suhre; Vikas O'Reilly-Shah; Wil Van Cleve


BMC Anesthesiol. 2020;20(115) 

In This Article


Patients who chronically use cannabis may be at increased risk of postoperative nausea and vomiting following general anesthesia. Further studies seeking to confirm and extend our findings could examine as to the symptoms being managed by cannabis use (if patients are using it medicinally). Furthermore, future studies would benefit from a finer grained understanding of patient's frequency, chronicity, route, and quantity of cannabis use, as well as whether the patient has experienced symptoms during abstention from cannabis use in the past. Finally, we believe it would be inappropriate on the basis of our study alone to recommend any modification in the approach to PONV prophylaxis for the chronic cannabis user, and encourage providers to wait for further data to integrate our findings into their clinical practice.