Does Fasting During Ramadan Increase the Risk of the Development of Sialadenitis?

Michael V. Joachim; Yasmine Ghantous; Suleiman Zaaroura; Kutaiba Alkeesh; Tameem Zoabi; Imad Abu el-Na'aj


BMC Oral Health. 2020;20(156) 

In This Article


Our data showed that 21 Muslims were admitted to the ER due to acute sialadenitis in the aforementioned hospitals during the 5 Ramadan months in the timeframe of the study, revealing an incidence of 4.2 cases/month (95% CI 2.641–6.176). This incidence was high compared to that during non-Ramadan months: 99 admissions due to acute sialadenitis in 55 non-Ramadan months, resulting in an incidence of 1.8 cases/month (95% CI 1.471–2.166). The risk ratio (RR) of ER admission due to acute sialadenitis during Ramadan was 2.33 (95% CI 1.46–3.72) and was statistically significant (p = 0.001). The curve for the prevalence of acute sialadenitis across months is presented in Figure 1.

Figure 1.

Prevalence of sialadenitis during the study

The variables and statistical analyses are detailed in Table 1. A comparison of blood test results from Ramadan vs. non-Ramadan sialadenitis patients revealed that Ramadan sialadenitis patients had significantly higher mean leucocyte numbers [*109/L] (8.98 ± 2.75 vs. 6.08 ± 4.78, p = 0.0085) and significantly higher mean creatinine [mg/dL] (0.81 ± 0.33 vs. 0.62 ± 0.13, p = 0.0001) and mean BUN [mg/dL] (14.26 ± 3.85 vs. 5 ± 2.08, p = 0.0001) levels. The combined mean BUN/creatinine ratio was significantly higher in Ramadan sialadenitis patients (17.7 vs. 8.06, p = 0.0001). There was no difference in amylase rates between Ramadan and non-Ramadan sialadenitis patients [U/L] (360 ± 405.25 vs. 370.25 ± 398.81, p = 0.915).

The mean age of Ramadan sialadenitis patients was 42.88 ± 16.7 years (SD, range 17–71), comparable to non-Ramadan sialadenitis patients whose mean age was 42.89 ± 22.02 years (SD, range 14–88). Additionally, there was no significant difference in M:F ratio or gland type affected between the two groups (Table 1).