Diffuse Large B Cell Lymphoma Involving Meckel's Cave Masquerading as Biopsynegative Giant Cell Arteritis

A Case Report

Matthew J. Samec; Andres G. Madrigal; Charlotte H. Rydberg; Matthew J. Koster


J Med Case Reports. 2020;14(57) 

In This Article


The diagnosis of giant cell arteritis (GCA) is based on clinical assessment of signs, symptoms, and laboratory features suggestive of the disease. Although non-invasive arterial imaging has shown increasing promise, the gold standard for diagnosis is confirmation through positive temporal artery biopsy (TAB).[1,2] Due to the lack of validated and approved diagnostic criteria for GCA, clinicians may inaccurately use criteria intended for research classification to diagnose this condition.[3] Here we describe a case of elevated inflammatory markers, frontal headache, and visions changes that was initially diagnosed as biopsy-negative GCA for which additional evaluation revealed a rare mimicking condition.