Successful Mastectomy and Chemotherapy in a Patient With Breast Cancer and Active Generalized Pyoderma Gangrenosum

Daniel C. Morse, MD; Payal M. Patel, MD; Carter Haag, MD; Alex G. Ortega-Loayza, MD


Wounds. 2020;32(4):E19-E22. 

In This Article


Diagnosis of PG can be challenging, as the clinical picture can be difficult to distinguish from other cutaneous infections when having a shock-like presentation. Interestingly, PG can be associated with comorbidities other than inflammatory bowel disease and rheumatoid arthritis, including solid malignancies, and certain chemotherapeutic drugs may predispose patients to developing PG. While there are a lack of guidelines for the perioperative management of PG, the authors have highlighted the pathergy dampening effect of IVIG in the perioperative management of patients with active PG to perform surgical procedures not related to PG itself.