Atopic Dermatitis and its Relation to Food Allergy

François Graham; Philippe A. Eigenmann


Curr Opin Allergy Clin Immunol. 2020;20(3):305-310. 

In This Article


Prebiotic and probiotic supplementations for the prevention of food allergy in children (with or without atopic dermatitis) are not currently recommended because of inconsistent evidence.[44,45] One recent study evaluated the effect of combining emollients and synbiotics (mixture of probiotics and prebiotics) alone or in combination from birth to the age of six months. Unfortunately, this strategy had no effect on prevention of food allergy at the age of one year.[71] On the other hand, a recent two-center randomized placebo-controlled trial showed that supplementation with Lactobacillus rhamnosus (HN0001) or Bifidobacterium lactis (HN019) during end of gestation, in breastfeeding mothers, and in infants till the age of two reduced the incidence of atopic disease including atopic dermatitis and food allergy at the age of 11.[72] Further data is needed. Finally, a recent systematic review concluded that there is insufficient data to support vitamin D supplementation to prevent atopic dermatitis and food allergy.[73]