Alternatives to Transfusion: A Case Report and Brief History of Artificial Oxygen Carriers

Sara Emily Bachert, MD; Prerna Dogra, MD; Leonard I. Boral, MD


Am J Clin Pathol. 2020;153(3):287-293. 

In This Article

Abstract and Introduction


Objectives: We discuss two main categories of blood substitutes: perfluorocarbons and hemoglobin-based oxygen carriers.

Methods: We provide a review of the notable products developed in both categories and include their attributes as well as their setbacks.

Results: We contribute a case report tothe growing literature of the successful use of Sanguinate.

Conclusions: We find that artificial oxygen carriers are an attractive field of research because of the practical limitations and the multitude of potential complications that surround human blood transfusions.