Comparison of Ropivacaine Combined With Sufentanil for Epidural Anesthesia and Spinal-epidural Anesthesia in Labor Analgesia

Results

There were no significant differences with regard to age, height, weight, BMI and duration of pregnancy between CSEA group and CEA group (P > 0.05) (Table 1).

VAS Scores in Two Groups

There was no significant differenceregarding VAS scores at T₀ between two groups (P > 0.05). In two groups, VAS scores at T₁, T₂ and T₃ were significantly lowercompared with T₀ in the same group (P < 0.01). VAS scores at T₁, T₂ and T₃ in CSEA group were significantly lower compared with those in CEA group at the same time (P < 0.01) (Table 2).

Labor Time in Two Groups

The onset time, T₁ and total labor time in CSEA group were significantly shorter than those in CEA group (P < 0.01). However, there was no significant difference regarding labor time at T₂ and T₃ between two groups (P > 0.05) (Table 3).

Apgar Scores in Two Groups

There were no significant differences in Apgar scores at 1, 5, and 10 min after birth between the two groups (P > 0.05) (Table 4).

Adverse Pregnancy Outcomes in Two Groups

There were no significant differences in adverse pregnancy outcomes after labor analgesia between the two groups (P > 0.05) (Table 5), including obstetric apparatus, cesarean, 24 h postpartum hemorrhage and episiotomy.

Doses of Drugs and Adverse Drug Reactions in Two Groups

Doses of ropivacaine and sufentanil in CSEA group were significantly lower than that in CEA group (P < 0.01) (Table 6). There were no significant differences in the rates of uroschesis and respiratory depression between two groups (P > 0.05). However, the rates of nausea, vomiting, pruritus and total adverse drug reactions in CSEA group were significantly lower than these in CEA group (P < 0.01). Besides, subject satisfaction in CSEA group were significantly higher than that in CEA group (P < 0.01) (Table 7).

BMC Anesthesiol. 2020;20(1) © 2020 BioMed Central, Ltd.