Conclusions
Advanced structural, molecular, and physiological imaging modalities have increased our ability to study the mechanisms of cSVDs in living individuals. Implementing and deploying these methods into carefully designed clinical studies will increase the yield in terms of diagnostic accuracy, risk stratification, and identification of new treatment targets.
Sources of Funding
This study was supported by the following funding agencies/grants: Dr Gurol receives support from grants National Institutes of Health (NIH) NS083711, 5R01NS096730-04, and 5R01AG026484; Dr Biessels receives support from European Union's Horizon 2020 research and innovation programme under grant agreement no. 666881 SVDs@target and Vici Grant 918.16.616 from the Netherlands Organization for Scientific Research; and Dr Polimeni receives support from grants NIH P41-EB015896, R01-EB019437, R01-NS096730, R01-MH111419, and by the Massachusetts General Hospital Athinoula A. Martinos Center for Biomedical Imaging.
Stroke. 2020;51(1):29-37. © 2020 American Heart Association, Inc.
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