Efficacy and Safety of Prophylactic Use of Ketamine for Prevention of Postanesthetic Shivering

A Systematic Review and Meta Analysis

Yang Zhou; Abdul Mannan; Yuan Han; He Liu; Hui-Lian Guan; Xing Gao; Ming-Sheng Dai; Jun-Li Cao


BMC Anesthesiol. 2019;19(245) 

In This Article


In this meta-analysis, we assessed various aspects of ketamine usage in controlling post-anaesthetic shivering. We found that ketamine reduced the incidence rate of shivering compared to the placebo. Although it is beneficial, it did not show any superiority over other pharmacological interventions. Ketamine is of clinical value, but further studies should be performed on a wider scale to determine more emphasized results. Furthermore, larger clinical trials investigating the combination of different anti-shivering regimens are warranted.